GALR2 Antikörper
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- Target Alle GALR2 Antikörper anzeigen
- GALR2 (Galanin Receptor 2 (GALR2))
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser GALR2 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Spezifität
- This antibody detects endogenous levels of GALR2 protein.(region surrounding Ile238)
- Aufreinigung
- Affinity Chromatography using epitope-specific immunogen.
- Top Product
- Discover our top product GALR2 Primärantikörper
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- Applikationshinweise
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ELISA: 1/40000approx. 1/60000. Western Blot: 1/500approx. 1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 1.0 mg/mL
- Buffer
- PBS, pH ~7.2, 15 mM Sodium Azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Target
- GALR2 (Galanin Receptor 2 (GALR2))
- Andere Bezeichnung
- GALR2 (GALR2 Produkte)
- Synonyme
- GALNR2 antikoerper, mGalR antikoerper, GALR2 antikoerper, GAL2-R antikoerper, GALR-2 antikoerper, galanin receptor 2 antikoerper, transcription regulator. LacI family, raffinose related antikoerper, DNA-binding transcriptional regulator GalR antikoerper, galactose operon repressor antikoerper, galanin receptor type 2 antikoerper, GALR2 antikoerper, Galr2 antikoerper, LOC100037698 antikoerper, rafR antikoerper, galR2 antikoerper, LOC103690156 antikoerper
- Hintergrund
- Galanin is an important neuromodulator present in the brain, gastrointestinal system, and hypothalamopituitary axis. It is a 30 amino acid non-C-terminally amidated peptide that potently stimulates growth hormone secretion, inhibits cardiac vagal slowing of heart rate, abolishes sinus arrhythmia, and inhibits postprandial gastrointestinal motility. The actions of galanin are mediated through interaction with specific membrane receptors that are members of the 7 transmembrane family of G protein coupled receptors. GALR2 interacts with the N terminal residues of the galanin peptide. The primary signaling mechanism for GALR2 is through the phospholipase C/protein kinase C pathway (via Gq), in contrast to GALR1, which communicates its intracellular signal by inhibition of adenylyl cyclase through Gi.Synonyms: GAL2-R, GALNR2, GALR-2, Galanin receptor type 2
- Molekulargewicht
- approx. 40.0 kDa
- Gen-ID
- 8811
- NCBI Accession
- NP_003848
- UniProt
- O43603
- Pathways
- cAMP Metabolic Process, Inositol Metabolic Process, Feeding Behaviour
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