EMR3 Antikörper

Produktnummer ABIN317634

Produktdetails anti-EMR3 Antikörper

Target: EMR3 (Egf-Like Module Containing, Mucin-Like, Hormone Receptor-Like 3 (EMR3))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser EMR3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Spezifität: This antibody detects endogenous levels of EMR3 protein.(region surrounding Tyr652)

Aufreinigung: Affinity Chromatography using epitope-specific immunogen.

Anwendungsinformationen

Applikationshinweise: ELISA: 1/10000-1/20000. Western Blot: 1/500-1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH ~7.2 containing 15 mM Sodium Azide as preservative.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu EMR3

Target: EMR3 (Egf-Like Module Containing, Mucin-Like, Hormone Receptor-Like 3 (EMR3))

Andere Bezeichnung: EMR3 (EMR3 Produkte)

Synonyme: EMR3 antikoerper, DKFZp459A1439 antikoerper, adhesion G protein-coupled receptor E3 antikoerper, ADGRE3 antikoerper, EMR3 antikoerper

Hintergrund: EMR3 is a member of the class B seven-span transmembrane (TM7) receptor family expressed predominantly by cells of the immune system. Family members are characterized by an extended extracellular region with a variable number of N-terminal epidermal growth factor (EGF)-like domains coupled to a TM7 domain via a mucin-like spacer domain. This gene is closely linked to the gene encoding egf-like molecule containing mucin-like hormone receptor 2 on chromosome 19. This protein may play a role in myeloid-myeloid interactions during immune and inflammatory responses. Alternative splicing of this gene results in two transcript variants encoding two distinct isoforms. EMR3 has been reported to be expressed in neutrophils, monocytes, and macrophages. ESTs have been isolated from liver/spleen and mixed libraries.Synonyms: EGF-like module receptor 3, EGF-like module-containing mucin-like hormone receptor-like 3

Gen-ID: 84658

NCBI Accession: NP_115960

UniProt: Q9BY15