ACVRL1 Antikörper

Produktnummer ABIN317607

Produktdetails anti-ACVRL1 Antikörper

Target: ACVRL1 (Activin A Receptor Type II-Like 1 (ACVRL1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ACVRL1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Spezifität: This antibody detects endogenous levels of ALK-1 protein (region surrounding Phe231)

Aufreinigung: Affinity Chromatography using epitope-specific immunogen

Anwendungsinformationen

Applikationshinweise: Western Blot: 1/500-1/1000. ELISA: 1/20000-1/40000. Immunohistochemistry: 1/50-1/200. Immunofluorescence: 1/50-1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS, pH ~7.2, 0.05 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu ACVRL1

Target: ACVRL1 (Activin A Receptor Type II-Like 1 (ACVRL1))

Andere Bezeichnung: ACVRL1 / ALK1 (ACVRL1 Produkte)

Synonyme: ACVRL1 antikoerper, vgb antikoerper, alk1 antikoerper, zehn1109 antikoerper, hm:zehn1109 antikoerper, ACVRLK1 antikoerper, ALK-1 antikoerper, ALK1 antikoerper, HHT antikoerper, HHT2 antikoerper, ORW2 antikoerper, SKR3 antikoerper, TSR-I antikoerper, R-3 antikoerper, R3 antikoerper, SETHKIR antikoerper, AI115505 antikoerper, AI427544 antikoerper, Acvrlk1 antikoerper, Alk1 antikoerper, activin A receptor like type 1 antikoerper, activin A receptor type II-like 1 antikoerper, activin A receptor, type II-like 1 antikoerper, ACVRL1 antikoerper, acvrl1 antikoerper, Acvrl1 antikoerper

Hintergrund: ACVRL1 is a type I cell-surface receptor for the TGF-beta superfamily of ligands. It shares with other type I receptors a high degree of similarity in serine-threonine kinase subdomains, a glycine- and serine-rich region (called the GS domain) preceding the kinase domain, and a short C-terminal tail. This protein, sometimes termed ALK1, shares similar domain structures with other closely related ALK or activin receptor-like kinase proteins that form a subfamily of receptor serine/threonine kinases. Mutations in this gene are associated with hemorrhagic telangiectasia type 2, also known as Rendu-Osler-Weber syndrome 2.Synonyms: ACVRLK1, Activin A receptor type II-like 1, Activin receptor-like kinase 1, SKR3, Serine/threonine-protein kinase receptor R3, TGF-B superfamily receptor type I

Molekulargewicht: approx. 56 kDa

Gen-ID: 94

NCBI Accession: NP_000011

UniProt: P37023