Tyrosine Hydroxylase Antikörper

Produktnummer ABIN308677

Produktdetails anti-Tyrosine Hydroxylase Antikörper

Target: Tyrosine Hydroxylase (TH)

Reaktivität: Human, Ratte, Maus, Protozoa

Wirt: Schaf

Klonalität: Polyklonal

Konjugat: Dieser Tyrosine Hydroxylase Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Kreuzreaktivität: Human, Maus, Primate, Ratte (Rattus)

Aufreinigung: affinity purified

Immunogen: Native rat tyrosine hydroxylase purified from pheochromocytoma.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Lagerung: -20 °C

Details zu Tyrosine Hydroxylase

Target: Tyrosine Hydroxylase (TH)

Andere Bezeichnung: Tyrosine Hydroxylase (TH Produkte)

Synonyme: DYT14 antikoerper, DYT5b antikoerper, TYH antikoerper, The antikoerper, CG10118 antikoerper, DH65B antikoerper, DTH antikoerper, Dmel\\CG10118 antikoerper, Pale antikoerper, Ple antikoerper, TH antikoerper, Th antikoerper, VII antikoerper, dTH1 antikoerper, dTH65B antikoerper, pale/ple antikoerper, th antikoerper, dyt14 antikoerper, dyt5b antikoerper, tyh antikoerper, tyrosine hydroxylase antikoerper, pale antikoerper, tyrosine 3-monooxygenase antikoerper, tyrosine hydroxylase S homeolog antikoerper, TH antikoerper, Th antikoerper, ple antikoerper, th antikoerper, th.S antikoerper, LOC100008895 antikoerper

Hintergrund: Tyrosine hydroxylase (TH) is the rate-limiting enzyme in the synthesis of the catecholamines dopamine, epinephrine and norepinephrine. Therefore the regulation of the TH enzyme represents the central means for controlling the synthesis of these important catecholamines. TH has a large molecular diversity, resulting from differential splicing of its mRNA, which is tissue specific and might result in long term changes in activity of the enzyme and the availability of neurotransmitter at various synapses. The presence of different DNA sequences at the TH locus confers susceptibility to various disorders of the brain including manic-depression and schizophrenia. Parkinson's disease is also considered a TH deficiency, as low dopamine levels are a consistent neurochemical abnormality.

Pathways: Dopaminergic Neurogenesis, Response to Water Deprivation, Sensory Perception of Sound, Carbohydrate Homeostasis, Feeding Behaviour