CACNA1I Antikörper

Produktnummer ABIN306882

Produktdetails anti-CACNA1I Antikörper

Target: CACNA1I (Calcium Channel, Voltage Dependent, T Type, alpha 1I Subunit (CACNA1I))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CACNA1I Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: This antibody can be used for Western blotting (5-10 ug/ml). Positive Control: Rat brain lysate.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/ml

Lagerung: -20 °C

Details zu CACNA1I

Target: CACNA1I (Calcium Channel, Voltage Dependent, T Type, alpha 1I Subunit (CACNA1I))

Andere Bezeichnung: Voltage-dependent T-type calcium channel subunit alpha-1I (CACNA1I Produkte)

Synonyme: CACNA1L antikoerper, Ca(V)3.3 antikoerper, Cav3.3 antikoerper, ca(v)3.3 antikoerper, si:ch211-51h13.1 antikoerper, Ca(v)3.3 antikoerper, calcium voltage-gated channel subunit alpha1 I antikoerper, voltage-dependent T-type calcium channel subunit alpha-1I antikoerper, calcium channel, voltage-dependent, alpha 1I subunit antikoerper, calcium channel, voltage-dependent, T type, alpha 1I subunit antikoerper, CACNA1I antikoerper, LOC100555412 antikoerper, Cacna1i antikoerper, cacna1i antikoerper

Hintergrund: Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. T-type channels serve pacemaking functions in both central neurons and cardiac nodal cells and support calcium signaling in secretory cells and vascular smooth muscle. They may also be involved in the modulation of firing patterns of neurons which is important for information processing as well as in cell growth processes. Using co-transfection techniques we investigated the functional effects of each of the gamma subunits on the biophysics of the T-type VSCC encoded by the alpha(1I) subunit. This revealed a substantially slowed rate of deactivation in the presence of gamma(2). In contrast, there was no significant corresponding effect of either gamma(3) or gamma(4) on alpha(1I) subunit-mediated currents.(2)Synonyms: Voltage-gated calcium channel subunit alpha Cav3.3,.

UniProt: Q9P0X4