PTGER3 Antikörper

Produktnummer ABIN306865

Produktdetails anti-PTGER3 Antikörper

Target: PTGER3 (Prostaglandin E Receptor 3 (Subtype EP3) (PTGER3))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser PTGER3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Kreuzreaktivität: Rind (Kuh), Human, Ratte

Produktmerkmale: Prostaglandin E2 Receptor Subtype EP3,Prostaglandins (PG's) are produced by the metabolism of arachidonic acid. PGE-2 is one of the five physiologically significant prostanoids known. Its wide spectrum of physiologic and pharmacologic effects in various tissues are mediated through binding to the PGE-2 receptors (EP1, EP2, EP3 & EP4). These include effects on the immune, endocrine, cardiovascular, renal and reproductive systems as well as smooth muscle. It is also one of the most abundant of the prostanoid family in the brain where it plays an important role in many neural functions, particularly in newborn babies, and as a mediator of inflammation. PGE-2 signals through a family of G-protein coupled receptors known as EP receptors. There are 4 subtypes of EP receptors, known as EP1, EP2, EP3 and EP4. EP3 receptors are 365-425 amino acid proteins. There are currently 4 known isoforms of EP3 receptors named EP3A, 3B, 3C and 3D. Each of has different physiological function, but differ only in the carboxyl terminus and how they couple to their respective G-proteins. EP3 receptors are involved in water absorption, gastric acid secretion, uterine contraction, neurotransmitter release and the hydrolysis of fat cells (lipolysis). EP3 receptors also act as a mediator of neural inflammation. These receptors are mainly localized in the brain, kidney, stomach, uterus and ovaries.

Aufreinigung: Protein A/G Chromatography

Immunogen: Hybridoma produced by the fusion of splenocytes from mice immunized with recombinant human EP3 receptor protein and mouse myeloma cells.

Klon: 5F5

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: This antibody can be used for Western blot analysis (1-5 μg/mL). Optimal concentration should be evaluated by serial dilutions.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Provided as solution in phosphate buffered saline with 0.08 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles

Details zu PTGER3

Target: PTGER3 (Prostaglandin E Receptor 3 (Subtype EP3) (PTGER3))

Andere Bezeichnung: Prostaglandin-E2 receptor EP3 (PTGER3 Produkte)

Synonyme: PTGER3 antikoerper, EP3 antikoerper, EP3-I antikoerper, EP3-II antikoerper, EP3-III antikoerper, EP3-IV antikoerper, EP3e antikoerper, PGE2-R antikoerper, PTGEREP3 antikoerper, Rep3 antikoerper, rEP3a antikoerper, rEP3b antikoerper, Pgerep3 antikoerper, Ptgerep3 antikoerper, prostaglandin E receptor 3 antikoerper, prostaglandin E receptor 3 L homeolog antikoerper, prostaglandin E receptor 3 (subtype EP3) antikoerper, PTGER3 antikoerper, ptger3.L antikoerper, Ptger3 antikoerper

UniProt: P34980