SERPINA3 Antikörper (Middle Region)

Produktnummer ABIN3044487

Produktdetails anti-SERPINA3 Antikörper

Target: SERPINA3 (serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 3 (SERPINA3))

Bindungsspezifität: AA 218-232, Middle Region

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SERPINA3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Verwendungszweck: Rabbit IgG polyclonal antibody for Alpha-1-antichymotrypsin(SERPINA3) detection. Tested with WB, IHC-P in Human.

Sequenz: EMPFDPQDTH QSRFY

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Produktmerkmale: Rabbit IgG polyclonal antibody for Alpha-1-antichymotrypsin(SERPINA3) detection. Tested with WB, IHC-P in Human.
Gene Name: serpin peptidase inhibitor, clade A(alpha-1 antiproteinase, antitrypsin), member 3
Protein Name: Alpha-1-antichymotrypsin

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence in the middle region of human alpha 1 Antichymotrypsin(218-232aa EMPFDPQDTHQSRFY).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Konservierungsmittel: Thimerosal (Merthiolate), Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu SERPINA3

Target: SERPINA3 (serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 3 (SERPINA3))

Andere Bezeichnung: SERPINA3 (SERPINA3 Produkte)

Synonyme: SERPINA3-1 antikoerper, Pi2 antikoerper, AACT antikoerper, ACT antikoerper, GIG25 antikoerper, A1AT antikoerper, PI antikoerper, alpha-1-PI antikoerper, AAT antikoerper, Pi antikoerper, Spi1 antikoerper, SERPINA3-5 antikoerper, serpina3 antikoerper, serpin A3-5 antikoerper, serpin family A member 3 antikoerper, alpha-1-antiproteinase F precursor antikoerper, serpin family A member 1 antikoerper, serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 antikoerper, serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 antikoerper, serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 L homeolog antikoerper, LOC396684 antikoerper, SERPINA3 antikoerper, LOC100008973 antikoerper, SERPINA1 antikoerper, Serpina1 antikoerper, SPIA5 antikoerper, serpina3.L antikoerper

Hintergrund: Alpha 1-antichymotrypsin, also called serpin peptidase inhibitor, clade A(alpha-1 antiproteinase, antitrypsin), member 3 or GIG24 is an alpha globulin glycoprotein that is a member of the serpin superfamily. In humans, it is encoded by the SERPINA3 gene. This gene is mapped to 14q32.13. The protein encoded by this gene is a plasma protease inhibitor and member of the serine protease inhibitor class. Polymorphisms in this protein appear to be tissue specific and influence protease targeting. Variations in this protein's sequence have been implicated in Alzheimer's disease, and deficiency of this protein has been associated with liver disease. Mutations have been identified in patients with Parkinson disease and chronic obstructive pulmonary disease.

Synonyms: SERPINA3 antibody|AACT antibody|AACT_HUMAN antibody|ACT antibody|Alpha 1 Antichymotrypsin 1 antibody|Alpha 1 Antichymotrypsin 2 antibody|Alpha 1 Antichymotrypsin 3 antibody|Alpha 1 Antitrypsin Deficiency antibody|Alpha-1-antichymotrypsin His-Pro-less antibody|Anti Elastase antibody|Antichymotrypsin antibody|Cell growth inhibiting gene 24/25 protein antibody|Cell growth-inhibiting gene 24/25 protein antibody|Clade A(Alpha 1 Antiproteinase Antitrypsin) antibody|GIG24 antibody|GIG25 antibody|Growth inhibiting protein 24 antibody|Growth inhibiting protein 25 antibody|MGC88254 antibody|PI1 antibody|Protease Inhibitor 1 antibody|Serine(or Cysteine) Proteinase Inhibitor antibody|Serine(or cysteine) proteinase inhibitor clade A(alpha 1 antiproteinase, antitrypsin) member 3 antibody|Serine(or cysteine) proteinase inhibitor clade A member 3 antibody|Serine proteinase inhibitor clade A member 3 antibody|Serpin A3 antibody|Serpin peptidase inhibitor clade A(alpha 1 antiproteinase antitrypsin) member 3 antibody|SERPINA1 antibody|SERPINA2 antibody|SERPINA3 antibody

UniProt: P01011