CHRM1 Antikörper (C-Term)

Produktnummer ABIN3044462

Produktdetails anti-CHRM1 Antikörper

Target: CHRM1 (Muscarinic Acetylcholine Receptor M1 (CHRM1))

Bindungsspezifität: AA 303-317, C-Term

Reaktivität: Ratte, Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CHRM1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Verwendungszweck: Rabbit IgG polyclonal antibody for Muscarinic acetylcholine receptor M1(CHRM1) detection. Tested with WB, IHC-P in Human,Mouse,Rat.

Sequenz: KMPMVDPEAQ APTKQ

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Produktmerkmale: Rabbit IgG polyclonal antibody for Muscarinic acetylcholine receptor M1(CHRM1) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
Gene Name: cholinergic receptor, muscarinic 1
Protein Name: Muscarinic acetylcholine receptor M1

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human muscarinic Acetylcholine Receptor 1(303-317aa KMPMVDPEAQAPTKQ), identical to the related mouse sequence, and different from the related rat sequence by one amino acid.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Rat, Predicted Species: Human, Mouse, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Konservierungsmittel: Thimerosal (Merthiolate), Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu CHRM1

Target: CHRM1 (Muscarinic Acetylcholine Receptor M1 (CHRM1))

Andere Bezeichnung: CHRM1 (CHRM1 Produkte)

Synonyme: M1 antikoerper, CHRM1 antikoerper, HM1 antikoerper, M1R antikoerper, mAChR antikoerper, Chrm-1 antikoerper, cholinergic receptor muscarinic 1 antikoerper, cholinergic receptor, muscarinic 1 antikoerper, cholinergic receptor, muscarinic 1, CNS antikoerper, CHRM1 antikoerper, Chrm1 antikoerper

Hintergrund: Muscarinic acetylcholine receptor M1, also known as cholinergic receptor, muscarinic 1, is a muscarinic receptor. This gene is mapped to 11q12.3. The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The muscarinic cholinergic receptor 1 is involved in mediation of vagally-induced bronchoconstriction and in the acid secretion of the gastrointestinal tract.

Synonyms: Cholinergic receptor muscarinic 1 antibody|CHRM 1 antibody|CHRM1 antibody|HM 1 antibody|HM1 antibody|M1 antibody|M1 muscarinic cholinergic receptor antibody|MGC30125 antibody|Muscarinic acetylcholine receptor M1 antibody

UniProt: P11229

Pathways: Synaptic Membrane