CAMKK1 Antikörper (N-Term)
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- Target Alle CAMKK1 Antikörper anzeigen
- CAMKK1 (Calcium/calmodulin-Dependent Protein Kinase Kinase 1, alpha (CAMKK1))
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Bindungsspezifität
- AA 10-31, N-Term
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser CAMKK1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Verwendungszweck
- Rabbit IgG polyclonal antibody for Calcium/calmodulin-dependent protein kinase kinase 1(CAMKK1) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
- Sequenz
- QDPRAELVDR VAAINVAHLE EA
- Kreuzreaktivität (Details)
- No cross reactivity with other proteins.
- Produktmerkmale
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Rabbit IgG polyclonal antibody for Calcium/calmodulin-dependent protein kinase kinase 1(CAMKK1) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
Gene Name: calcium/calmodulin-dependent protein kinase kinase 1, alpha
Protein Name: Calcium/calmodulin-dependent protein kinase kinase 1(CaM-KK 1/CaM-kinase kinase 1/CaMKK 1) - Aufreinigung
- Immunogen affinity purified.
- Immunogen
- A synthetic peptide corresponding to a sequence at the N-terminus of mouse CaMKK(10-31aa QDPRAELVDRVAAINVAHLEEA), different from the related human sequence by three amino acids, and from the related rat sequence by two amino acids.
- Isotyp
- IgG
- Top Product
- Discover our top product CAMKK1 Primärantikörper
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- Applikationshinweise
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Rat, Predicted Species: Mouse, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users. - Kommentare
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- Konzentration
- 500 μg/mL
- Buffer
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
- Konservierungsmittel
- Thimerosal (Merthiolate), Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing. - Haltbarkeit
- 12 months
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- Target
- CAMKK1 (Calcium/calmodulin-Dependent Protein Kinase Kinase 1, alpha (CAMKK1))
- Andere Bezeichnung
- CAMKK1 (CAMKK1 Produkte)
- Synonyme
- cam-kk antikoerper, cam-kk1 antikoerper, camkka antikoerper, zgc:113440 antikoerper, CAMKK1 antikoerper, CaM-KK antikoerper, CAMKKA antikoerper, AI846603 antikoerper, CaMKKalpha antikoerper, Camkk antikoerper, calcium/calmodulin-dependent protein kinase kinase 1 S homeolog antikoerper, calcium/calmodulin dependent protein kinase kinase 1 antikoerper, calcium/calmodulin-dependent protein kinase kinase 1, alpha a antikoerper, calcium/calmodulin-dependent protein kinase kinase 1 antikoerper, calcium/calmodulin-dependent protein kinase kinase 1, alpha antikoerper, camkk1.S antikoerper, CAMKK1 antikoerper, camkk1a antikoerper, camkk1 antikoerper, Camkk1 antikoerper
- Hintergrund
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CAMKK1, Calcium/calmodulin-dependent protein kinase kinase 1 is an enzyme that in humans is encoded by the CAMKK1 gene. The CAMKK1 gene is mapped to chromosome 17. The product of this gene belongs to the Serine/Threonine protein kinase family, and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. This protein plays a role in the calcium/calmodulin-dependent(CaM) kinase cascade. Three transcript variants encoding two distinct isoforms have been identified for this gene.Camkk1binds calmodulin and activated Camk4 with a 6-fold increase in total activity and a 100-fold increase in Camk4 Ca(2+)-independent activity. Camkk1 catalyzed a 10-fold increase in the total activity of Camk1 and had no effect on Camk2. Cotransfection of COS-7 cells with Camkk1 and Camk4 resulted in a 14-fold increase in CRE-binding protein-dependent transcription compared with Camk4 alone, suggesting that Camkk1 enhances Camk4-mediated transcriptional regulation.
Synonyms: Ca2+/calmodulin-dependent protein kinase kinase alpha antibody|Calcium/calmodulin dependent protein kinase kinase antibody|Calcium/calmodulin dependent protein kinase kinase 1 alpha antibody|Calcium/calmodulin dependent protein kinase kinase 1 antibody|Calcium/calmodulin dependent protein kinase kinase alpha antibody|Calcium/calmodulin-dependent protein kinase kinase 1 antibody|Calcium/calmodulin-dependent protein kinase kinase alpha antibody|CaM kinase kinase alpha antibody|CaM-kinase IV kinase antibody|CaM-kinase kinase 1 antibody|CaM-kinase kinase alpha antibody|CaM-KK 1 antibody|CaM-KK alpha antibody|CaMKK 1 antibody|CaMKK alpha antibody|CAMKK alpha protein antibody|CaMKK antibody|CAMKK1 antibody|CAMKKA antibody|DKFZp761M0423 antibody|KKCC1_HUMAN antibody|MGC34095 antibody|OTTMUSP00000006419 antibody - Pathways
- AMPK Signaling
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