BMPR1B Antikörper (Middle Region)

Produktnummer ABIN3044052

Produktdetails anti-BMPR1B Antikörper

Target: BMPR1B (Bone Morphogenetic Protein Receptor, Type IB (BMPR1B))

Bindungsspezifität: AA 145-160, Middle Region

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BMPR1B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Verwendungszweck: Rabbit IgG polyclonal antibody for Bone morphogenetic protein receptor type-1B(BMPR1B) detection. Tested with WB in Human,Mouse,Rat.

Sequenz: FCYFRYKRQE TRPRYS

Kreuzreaktivität (Details): Predicted Cross Reactivity: mouse, rat
No cross reactivity with other proteins.
Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities.

Produktmerkmale: Rabbit IgG polyclonal antibody for Bone morphogenetic protein receptor type-1B(BMPR1B) detection. Tested with WB in Human,Mouse,Rat.
Gene Name: bone morphogenetic protein receptor, type IB
Protein Name: Bone morphogenetic protein receptor type-1B

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence in the middle region of human BMPR1B(145-160aa FCYFRYKRQETRPRYS), different from the related rat and mouse sequences by one amino acid.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Predicted Species: Mouse, Rat, The detection limit for BMPR1B is approximately 0.5 ng/lane under reducing conditions.
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Konservierungsmittel: Thimerosal (Merthiolate), Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu BMPR1B

Target: BMPR1B (Bone Morphogenetic Protein Receptor, Type IB (BMPR1B))

Andere Bezeichnung: BMPR1B (BMPR1B Produkte)

Synonyme: ALK6 antikoerper, BMPR-IB antikoerper, FecB antikoerper, alk-6 antikoerper, alk6 antikoerper, cdw293 antikoerper, alk6b antikoerper, zgc:172219 antikoerper, BMPR1B antikoerper, AI385617 antikoerper, ALK-6 antikoerper, AV355320 antikoerper, Acvrlk6 antikoerper, Alk6 antikoerper, BMPR-1B antikoerper, CFK-43a antikoerper, SKR6 antikoerper, BR1b antikoerper, alk6tr antikoerper, bmpr1b antikoerper, zALK-6 antikoerper, zgc:92220 antikoerper, CDw293 antikoerper, BMP15 antikoerper, BMPRIB antikoerper, RPK-1 antikoerper, bone morphogenetic protein receptor type 1B antikoerper, bone morphogenetic protein receptor, type IBb antikoerper, bone morphogenetic protein receptor, type 1B antikoerper, bone morphogenetic protein receptor, type IBa antikoerper, BMPR1B antikoerper, bmpr1b antikoerper, bmpr1bb antikoerper, Bmpr1b antikoerper, bmpr1ba antikoerper

Hintergrund: BMPR1B(Bone Morphogenetic Protein Receptor Type IB), also known as ALK6, is a protein which in humans is encoded by the BMPR1B gene. BMPR1B is a member of the bone morphogenetic protein(BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs, which are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of 2 different types of serine(threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. By analysis of a monochromosome hybrid mapping panel and by FISH, Astrom et al.(1999) mapped the BMPR1B gene to chromosome 4q22-q24. Ide et al.(1997) compared BMP receptor expression in normal and cancerous prostate tissues. While BMPR1A and BMPR2 were expressed at similar levels in all prostate tissues, BMPR1B was expressed at a significantly reduced level in cancerous prostate tissue.

Synonyms: Activin receptor like kinase 6 antibody|Acvrlk6 antibody|ALK 6 antibody|ALK6 antibody|alk6tr antibody|BMP type-1B receptor antibody|BMPR IB antibody|BMPR-1B antibody|Bmpr1b antibody|BMPRIB antibody|BMR1B_HUMAN antibody|Bone morphogenetic protein receptor type 1B antibody|Bone morphogenetic protein receptor type IB antibody|Bone morphogenetic protein receptor type-1B antibody|BR 1b antibody|BR1b antibody|CDw 293 antibody|CDw293 antibody|CDw293 antigen antibody|CFK 43a antibody|CFK43a antibody|Serine/threonine receptor kinase antibody|zALK 6 antibody|zALK6 antibody

UniProt: O00238