TRPV2 Antikörper (N-Term)

Produktnummer ABIN3044039

Produktdetails anti-TRPV2 Antikörper

Target: TRPV2 (Transient Receptor Potential Cation Channel, Subfamily V, Member 2 (TRPV2))

Bindungsspezifität: AA 42-624, N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TRPV2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Verwendungszweck: Rabbit IgG polyclonal antibody for Transient receptor potential cation channel subfamily V member 2(TRPV2) detection. Tested with WB, IHC-P, IHC-F in Human.

Sequenz: QFQGEDRKFA PQIRVNLNYR K

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Produktmerkmale: Rabbit IgG polyclonal antibody for Transient receptor potential cation channel subfamily V member 2(TRPV2) detection. Tested with WB, IHC-P, IHC-F in Human.
Gene Name: transient receptor potential cation channel, subfamily V, member 2
Protein Name: Transient receptor potential cation channel subfamily V member 2

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human VRL1(42-624aa QFQGEDRKFAPQIRVNLNYRK).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, The detection limit for TRPV2 is approximately 0.5 ng/lane under reducing conditions.
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
IHC-F: Concentration: 0.5-1 μg/mL, Tested Species: Human
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P) and IHC(F).

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Konservierungsmittel: Thimerosal (Merthiolate), Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu TRPV2

Target: TRPV2 (Transient Receptor Potential Cation Channel, Subfamily V, Member 2 (TRPV2))

Andere Bezeichnung: TRPV2 (TRPV2 Produkte)

Synonyme: TRPV2 antikoerper, VRL antikoerper, VRL-1 antikoerper, VRL1 antikoerper, Vrl1 antikoerper, GRC antikoerper, OTRPC2 antikoerper, transient receptor potential cation channel subfamily V member 2 antikoerper, transient receptor potential cation channel, subfamily V, member 2 antikoerper, TRPV2 antikoerper, LOC100540299 antikoerper, Trpv2 antikoerper

Hintergrund: TRPV2(Transient Receptor Potential Cation Channel Subfamily V Member 2), also known as VRL1, is a protein that, in humans, is encoded by the TRPV1 gene. The International Radiation Hybrid Mapping Consortium mapped the TRPV2 gene to chromosome 17. This gene encodes an ion channel that is activated by high temperatures above 52 °C. The protein may be involved in transduction of high-temperature heat responses in sensory ganglia. It is though that in other tissues the channel may be activated by stimuli other than heat.

Synonyms: MGC12549 antibody|Osm 9 like TRP channel 2 antibody|osm-9-like TRP channel 2 antibody|OTRPC2 antibody|Sac2b antibody|Sac2b(gene name) antibody|Stretch activated channel 2B antibody|Stretch-activated channel 2B antibody|Transient receptor potential cation channel subfamily V member 2 antibody|TrpV2 antibody|TRPV2_HUMAN antibody|Vanilloid receptor like protein 1 antibody|Vanilloid receptor-like protein 1 antibody|VRL 1 antibody|VRL antibody|VRL-1 antibody|VRL1 antibody

UniProt: Q9Y5S1

Pathways: Regulation of Cell Size