NRIP1 Antikörper (N-Term)

Produktnummer ABIN3043581

Produktdetails anti-NRIP1 Antikörper

Target: NRIP1 (Nuclear Receptor Interacting Protein 1 (NRIP1))

Bindungsspezifität: AA 273-306, N-Term

Reaktivität: Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NRIP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Verwendungszweck: Rabbit IgG polyclonal antibody for Nuclear receptor-interacting protein 1(NRIP1) detection. Tested with WB in Human,Mouse,Rat.

Sequenz: EAHLQQYSRE HALKTQNANQ AASERLAAMA RLQE

Kreuzreaktivität (Details): Predicted Cross Reactivity: human
No cross reactivity with other proteins.
Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities.

Produktmerkmale: Rabbit IgG polyclonal antibody for Nuclear receptor-interacting protein 1(NRIP1) detection. Tested with WB in Human,Mouse,Rat.
Gene Name: nuclear receptor interacting protein 1
Protein Name: Nuclear receptor-interacting protein 1

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human RIP140 (273-306aa EAHLQQYSREHALKTQNANQAASERLAAMARLQE), different from the related mouse sequence by two amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Mouse, Rat, Predicted Species: Human
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Details zu NRIP1

Target: NRIP1 (Nuclear Receptor Interacting Protein 1 (NRIP1))

Andere Bezeichnung: NRIP1 (NRIP1 Produkte)

Synonyme: MGC68665 antikoerper, NRIP1 antikoerper, RIP140 antikoerper, 6030458L20Rik antikoerper, 8430438I05Rik antikoerper, 9630050P12 antikoerper, AA959574 antikoerper, AW456757 antikoerper, nuclear receptor interacting protein 1 S homeolog antikoerper, nuclear receptor interacting protein 1 antikoerper, circumsporozoite protein antikoerper, nrip1.S antikoerper, NRIP1 antikoerper, nrip1 antikoerper, Nrip1 antikoerper, LOC100627733 antikoerper

Hintergrund: Nuclear receptor-interacting protein 1 (NRIP1), also known as receptor-interacting protein 140 (RIP140), is a protein that in humans is encoded by the NRIP1 gene. It is a nuclear protein that specifically interacts with the hormone-dependent activation domain AF2 of nuclear receptors. Also known as RIP140, this protein is a key regulator which modulates transcriptional activity of a variety of transcription factors, including the estrogen receptor. RIP140 has an important role in regulating lipid and glucose metabolism, and regulates gene expression in metabolic tissues including heart, skeletal muscle, and liver. A major role for RIP140 in adipose tissue is to block the expression of genes involved in energy dissipation and mitochondrial uncoupling, including uncoupling protein 1 and carnitine palmitoyltransferase 1b.

Synonyms: NRIP 1 antibody|NRIP1 antibody|NRIP1_HUMAN antibody|Nuclear factor RIP 140 antibody|Nuclear factor RIP140 antibody|Nuclear receptor interacting protein 1 antibody|Nuclear receptor-interacting protein 1 antibody|Receptor interacting protein 140 antibody|Receptor-interacting protein 140 antibody|RIP 140 antibody|RIP140 antibody

Gen-ID: 8204

UniProt: P48552

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway