SPI1 Antikörper (AA 18-196)

Produktnummer ABIN3043440

Produktdetails anti-SPI1 Antikörper

Target: SPI1 (Spleen Focus Forming Virus (SFFV) Proviral Integration Oncogene Spi1 (SPI1))

Bindungsspezifität: AA 18-196

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SPI1 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Verwendungszweck: Rabbit IgG polyclonal antibody for Transcription factor PU.1(SPI1) detection. Tested with IHC-P in Human,Mouse,Rat.

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Produktmerkmale: Rabbit IgG polyclonal antibody for Transcription factor PU.1(SPI1) detection. Tested with IHC-P in Human,Mouse,Rat.
Gene Name: Spi-1 proto-oncogene
Protein Name: Transcription factor PU.1

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human PU.1/Spi1 recombinant protein (Position: E18-K196). Human PU.1/Spi1 shares 84% and 84.4% amino acid (aa) sequence identity with mouse and rat PU.1/Spi1, respectively.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Kommentare:

Antibody can be supported by ABIN921231 in IHC(P).

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Details zu SPI1

Target: SPI1 (Spleen Focus Forming Virus (SFFV) Proviral Integration Oncogene Spi1 (SPI1))

Andere Bezeichnung: SPI1 (SPI1 Produkte)

Synonyme: OF antikoerper, PU.1 antikoerper, SFPI1 antikoerper, SPI-1 antikoerper, SPI-A antikoerper, Dis-1 antikoerper, Dis1 antikoerper, Sfpi-1 antikoerper, Sfpi1 antikoerper, Spi-1 antikoerper, Tcfpu1 antikoerper, Tfpu.1 antikoerper, Pu.1 antikoerper, cb1086 antikoerper, pu.1 antikoerper, pu1 antikoerper, sfpi1 antikoerper, si:by184l24.2 antikoerper, spi1 antikoerper, SPI1/PU.1 antikoerper, spi1l antikoerper, zgc:152991 antikoerper, Spi-1 proto-oncogene antikoerper, spleen focus forming virus (SFFV) proviral integration oncogene antikoerper, Spi-1 proto-oncogene b antikoerper, Spi-1 proto-oncogene a antikoerper, SPI1 antikoerper, Spi1 antikoerper, spi1b antikoerper, spi1a antikoerper

Hintergrund: Transcription factor PU.1 is a protein that in humans is encoded by the SPI1 gene. This gene encodes an ETS-domain transcription factor that activates gene expression during myeloid and B-lymphoid cell development. The nuclear protein binds to a purine-rich sequence known as the PU-box found near the promoters of target genes, and regulates their expression in coordination with other transcription factors and cofactors. The protein can also regulate alternative splicing of target genes. Multiple transcript variants encoding different isoforms have been found for this gene.

Synonyms: 31 kDa Transforming Protein antibody|31 kDa-transforming protein antibody|Hematopoietic transcription factor PU.1 antibody|OF antibody|PU.1 antibody|SFPI1 antibody|SPI 1 proto oncogene antibody|SPI A antibody|Spi1 antibody|SPI1_HUMAN antibody|Spleen focus forming virus (SFFV) proviral integration oncogene spi1 antibody|Transcription factor PU.1 antibody

Gen-ID: 6688

UniProt: P17947

Pathways: Stem Cell Maintenance