P2RX4 Antikörper (AA 262-388)

Produktnummer ABIN3043376

Produktdetails anti-P2RX4 Antikörper

Target: P2RX4 (Purinergic Receptor P2X, Ligand-Gated Ion Channel, 4 (P2RX4))

Bindungsspezifität: AA 262-388

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser P2RX4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Verwendungszweck: Rabbit IgG polyclonal antibody for P2X purinoceptor 4(P2RX4) detection. Tested with WB in Human.

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Produktmerkmale: Rabbit IgG polyclonal antibody for P2X purinoceptor 4(P2RX4) detection. Tested with WB in Human.
Gene Name: purinergic receptor P2X, ligand gated ion channel, 4
Protein Name: P2X purinoceptor 4

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human P2RX4 recombinant protein (Position: N262-Q388). Human P2RX4 shares 91% and 90% amino acid (aa) sequence identity with mouse and rat P2RX4, respectively.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, The detection limit for P2RX4 is approximately 0.25 ng/lane under reducing conditions.
Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Details zu P2RX4

Target: P2RX4 (Purinergic Receptor P2X, Ligand-Gated Ion Channel, 4 (P2RX4))

Andere Bezeichnung: P2RX4 (P2RX4 Produkte)

Synonyme: P2X4 antikoerper, P2X4R antikoerper, AI504491 antikoerper, AW555605 antikoerper, D5Ertd444e antikoerper, p2rx4 antikoerper, p2x4 antikoerper, wu:fi03f02 antikoerper, p2x4r antikoerper, p2rx4.2 antikoerper, p2xr4.2 antikoerper, purinergic receptor P2X 4 antikoerper, purinergic receptor P2X, ligand-gated ion channel 4 antikoerper, purinergic receptor P2X, ligand-gated ion channel, 4a antikoerper, purinergic receptor P2X, ligand gated ion channel, 4 L homeolog antikoerper, purinergic receptor P2X, ligand-gated ion channel, 4b antikoerper, P2RX4 antikoerper, P2rx4 antikoerper, p2rx4a antikoerper, p2rx4.L antikoerper, p2rx4b antikoerper

Hintergrund: Purinoceptor P2X4, also called P2X4R is a protein that in humans is encoded by the P2RX4 gene. This gene belongs to the family of purinoceptors for ATP. P2RX4 was mapped to 12q24.32 by fluorescence in situ hybridization. P2RX4 is a receptor for ATP that acts as a ligand-gated ion channel. This receptor is insensitive to the antagonists PPADS and suramin. P2X4 receptor in hyperactive microglia is necessary for tactile allodynia after nerve injury and is sufficient to produce tactile allodynia in normal animals. P2X4 recetors have beeb implicated in the regulation of cardiac function, ATP-mediated cell death, synaptic strengthening, and activating of the inflammasome in response to injury.

Synonyms: AI504491 antibody|ATP gated cation channel protein antibody|ATP receptor antibody|AW555605 antibody|D5Ertd444e antibody|MGC143034 antibody|OTTMUSP00000023741 antibody|OTTMUSP00000023745 antibody|OTTMUSP00000023746 antibody|OTTMUSP00000023747 antibody|p2rx4 antibody|P2RX4_HUMAN antibody|P2X purinoceptor 4 antibody|P2X receptor subunit 4 antibody|P2X4 antibody|P2X4R antibody|Purinergic receptor antibody|Purinergic receptor P2X ligand gated ion channel 4 antibody|Purinergic receptor P2X4 antibody|Purinoceptor P2X4 antibody

Gen-ID: 5025

UniProt: Q99571

Pathways: Synaptic Membrane