TXNRD2 Antikörper (C-Term)

Produktnummer ABIN3043001

Produktdetails anti-TXNRD2 Antikörper

Target: TXNRD2 (Thioredoxin Reductase 2 (TXNRD2))

Bindungsspezifität: AA 418-434, C-Term

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TXNRD2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Verwendungszweck: Rabbit IgG polyclonal antibody for Thioredoxin reductase 2, mitochondrial(TXNRD2) detection. Tested with WB, IHC-P in Human,Rat.

Sequenz: RHGQEHVEVY HAHYKPL

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Produktmerkmale: Rabbit IgG polyclonal antibody for Thioredoxin reductase 2, mitochondrial(TXNRD2) detection. Tested with WB, IHC-P in Human,Rat.
Gene Name: thioredoxin reductase 2
Protein Name: Thioredoxin reductase 2, mitochondrial

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human TXNRD2(418-434aa RHGQEHVEVYHAHYKPL), different from the related rat sequence by three amino acids, and from the related mouse sequence by two amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Konservierungsmittel: Thimerosal (Merthiolate), Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu TXNRD2

Target: TXNRD2 (Thioredoxin Reductase 2 (TXNRD2))

Andere Bezeichnung: TXNRD2 (TXNRD2 Produkte)

Synonyme: CG11401 antikoerper, Dm-TrxR antikoerper, DmTrx antikoerper, DmTrxR-2 antikoerper, Dmel\\CG11401 antikoerper, Trxr2 antikoerper, trxr-2 antikoerper, SELZ antikoerper, TR antikoerper, TR-BETA antikoerper, TR3 antikoerper, TRXR2 antikoerper, AA118373 antikoerper, ESTM573010 antikoerper, TGR antikoerper, Tr3 antikoerper, Trxrd2 antikoerper, thioredoxin reductase 2 antikoerper, Trxr-2 antikoerper, TXNRD2 antikoerper, Txnrd2 antikoerper

Hintergrund: TXNRD2(Thioredoxin reductase 2), also known as TRXR2, TR3, SELZ, or TR-BETA, Thioredoxin reductases, are selenocysteine(sec)-containing flavoenzymes that maintain thioredoxins, small proteins that catalyze redox reactions, in the reduced state using the reducing power of NADPH. By STS analysis and genomic sequence analysis, respectively, Miranda-Vizuete et al.(1999) and Sun et al.(1999) mapped the TXNRD2 gene to chromosome 22q11.2. Miranda-Vizuete et al.(1999) mapped the mouse gene to chromosome 16. Gasdaska et al.(1999) showed that TXNRD2 was a thioredoxin reductase that could directly reduce proteins such as insulin.

Synonyms: mitochondrial antibody|selenoprotein Z antibody|SELZ antibody|Thioredoxin reductase 2 antibody|Thioredoxin reductase 2 mitochondrial antibody|thioredoxin reductase 3 antibody|thioredoxin reductase beta antibody|Thioredoxin reductase TR3 antibody|TR 3 antibody|TR antibody|TR beta antibody|TR-beta antibody|TR3 antibody|TRXR 2 antibody|TRXR2 antibody|TRXR2_HUMAN antibody|TXNRD 2 antibody|Txnrd2 antibody

Pathways: Cell RedoxHomeostasis