IRF8 Antikörper (C-Term)

Produktnummer ABIN3042833

Produktdetails anti-IRF8 Antikörper

Target: IRF8 (Interferon Regulatory Factor 8 (IRF8))

Bindungsspezifität: AA 411-426, C-Term

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IRF8 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Verwendungszweck: Rabbit IgG polyclonal antibody for Interferon regulatory factor 8(IRF8) detection. Tested with WB in Human,Mouse,Rat.

Sequenz: ASHQRSFFRE NQQITV

Kreuzreaktivität (Details): Predicted Cross Reactivity: mouse
No cross reactivity with other proteins.
Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities.

Produktmerkmale: Rabbit IgG polyclonal antibody for Interferon regulatory factor 8(IRF8) detection. Tested with WB in Human,Mouse,Rat.
Gene Name: interferon regulatory factor 8
Protein Name: Interferon regulatory factor 8

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human IRF8(411-426aa ASHQRSFFRENQQITV), different from the related mouse and rat sequences by two amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Konservierungsmittel: Thimerosal (Merthiolate), Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu IRF8

Target: IRF8 (Interferon Regulatory Factor 8 (IRF8))

Andere Bezeichnung: IRF8 (IRF8 Produkte)

Synonyme: zgc:92252 antikoerper, IRF8 antikoerper, MGC140338 antikoerper, DKFZp469B0320 antikoerper, H-ICSBP antikoerper, ICSBP antikoerper, ICSBP1 antikoerper, IRF-8 antikoerper, icsbp1 antikoerper, AI893568 antikoerper, Icsbp1 antikoerper, Myls antikoerper, interferon regulatory factor 8 antikoerper, interferon regulatory factor 8 L homeolog antikoerper, irf8 antikoerper, IRF8 antikoerper, irf8.L antikoerper, Irf8 antikoerper

Hintergrund: Interferon regulatory factor 8(IRF8) also known as Interferon consensus sequence-binding protein(ICSBP), is a protein that in humans is encoded by the IRF8 gene. By genomic sequence analysis, the IRF8 gene is mapped to chromosome 16q24.1. Interferon consensus sequence-binding protein(ICSBP) is a transcription factor of the interferon(IFN) regulatory factor(IRF) family. The IRF family proteins bind to the IFN-stimulated response element(ISRE) and regulate expression of genes stimulated by type I IFNs, namely IFN-alpha and IFN-beta. IRF family proteins also control expression of IFN-alpha and IFN-beta-regulated genes that are induced by viral infection. IRF8 is a transcription factor that plays critical roles in the regulation of lineage commitment and in myeloid cell maturation including the decision for a common myeloid progenitor(CMP) to differentiate into a monocyte precursor cell.

Synonyms: H ICSBP antibody|H-ICSBP antibody|HGNC:5358 antibody|HGNC5358 antibody|HICSBP antibody|ICSBP 1 antibody|ICSBP antibody|ICSBP1 antibody|Interferon Consensus Sequence Binding Protein 1 antibody|Interferon consensus sequence binding protein antibody|Interferon consensus sequence-binding protein antibody|Interferon Regulatory Factor 8 antibody|IRF 8 antibody|IRF-8 antibody|IRF8 antibody|IRF8_HUMAN antibody|MYLS antibody

UniProt: Q02556

Pathways: Cellular Response to Molecule of Bacterial Origin