SSTR2 Antikörper (Middle Region)

Produktnummer ABIN3032694

Produktdetails anti-SSTR2 Antikörper

Target: SSTR2 (Somatostatin Receptor 2 (SSTR2))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SSTR2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: Antigen affinity

Immunogen: An amino acid sequence from the middle region of human Somatostatin Receptor 2 (RSNQWGRSSCTINWP) was used as the immunogen for this SSTR2 antibody (100% homologous in human, mouse and rat).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: The stated application concentrations are suggested starting amounts. Titration of the SSTR2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: -20 °C

Informationen zur Lagerung: After reconstitution, the SSTR2 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Details zu SSTR2

Target: SSTR2 (Somatostatin Receptor 2 (SSTR2))

Andere Bezeichnung: SSTR2 Somatostatin Receptor 2 (SSTR2 Produkte)

Synonyme: Smstr2 antikoerper, SSTR-2 antikoerper, Smstr-2 antikoerper, sst2 antikoerper, SS2R antikoerper, SSTR2 antikoerper, MGC80373 antikoerper, somatostatin receptor 2 antikoerper, somatostatin receptor 2 L homeolog antikoerper, SSTR2 antikoerper, Sstr2 antikoerper, sstr2.L antikoerper

Hintergrund: Somatostatin receptor type 2 is a protein that in humans is encoded by the SSTR2 gene. Somatostatin acts at many sites to inhibit the release of many hormones and other secretory proteins. The biologic effects of somatostatin are probably mediated by a family of G protein-coupled receptors that are expressed in a tissue-specific manner. SSTR2 is a member of the superfamily of receptors having seven transmembrane segments and is expressed in highest levels in cerebrum and kidney. Stable transfection of human pancreatic cells, which do not endogenously express SSTR2, inhibits cell proliferation, tumorigenicity, and metastasis. These effects occur as a consequence of an autocrine SSTR2-dependent loop, whereby SSTR2 induces expression of its own ligand, somatostatin. mRNA was variably expressed in all neuroblastoma tumors with a relevant reduction in the more advanced stage.

UniProt: P30874