FAIM2 Antikörper (N-Term)

Produktnummer ABIN303262

Produktdetails anti-FAIM2 Antikörper

Target: FAIM2 (Fas Apoptotic Inhibitory Molecule 2 (FAIM2))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FAIM2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität: Recognizes 16 amino acid peptide from near the amino terminus of Human LFG.

Kreuzreaktivität (Details): Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.

Aufreinigung: Immunoaffinity Chromatography.

Immunogen: Synthetic Peptide corresponding to 16 amino acid peptide from near the amino terminus of human LFG.

Anwendungsinformationen

Applikationshinweise: Immunohistochemistry on Paraffin Sections (5 μg/mL). Western Blot.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % Sodium Azide as preservative.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer. Dilute only prior to immediate use.

Details zu FAIM2

Target: FAIM2 (Fas Apoptotic Inhibitory Molecule 2 (FAIM2))

Andere Bezeichnung: FAIM2 (FAIM2 Produkte)

Synonyme: FAIM2 antikoerper, faim2 antikoerper, MGC84041 antikoerper, zgc:110143 antikoerper, MGC146456 antikoerper, LFG antikoerper, LFG2 antikoerper, NGP35 antikoerper, NMP35 antikoerper, TMBIM2 antikoerper, 2900002L20Rik antikoerper, Lfg antikoerper, Lfg2 antikoerper, NMP25 antikoerper, Nmp35 antikoerper, Fas apoptotic inhibitory molecule 2 antikoerper, Fas apoptotic inhibitory molecule 2 L homeolog antikoerper, Fas apoptotic inhibitory molecule 2a antikoerper, fas apoptotic inhibitory molecule 2 antikoerper, FAIM2 antikoerper, faim2 antikoerper, faim2.L antikoerper, faim2a antikoerper, CpipJ_CPIJ015441 antikoerper, Faim2 antikoerper

Hintergrund: Programmed cell death regulates a number of biological processes such as normal organism development, tissue homeostasis, and removal of damaged cells. Disruption of this process has been implicated in a variety of diseases such as cancer. FAIM2 is a recently identified protein that can inhibit the apoptotic signal transduced by the Fas receptor but not from the related tumor necrosis factor-alpha death signal. In this respect, FAIM2 is functionally similar to the anti-apoptotic proteins FAIM, FLIP and Bcl-xL. FAIM2, a seven membrane spanning protein, can bind the Fas receptor but does not regulate Fas expression or inhibit binding of FADD to Fas. FAIM2 is widely distributed, but highly expressed in the hippocampus and other neural tissues. FAIM2 was also identified as the neural membrane protein 35 (NMP35) and its expression is known to be regulated by the Phosphatidylinositol 3-kinase-Akt/PKB pathway.Synonyms: Fas apoptotic inhibitory molecule 2, KIAA0950, LFG, Protein lifeguard, TMBIM2, Transmembrane BAX inhibitor motif-containing protein 2

Gen-ID: 23017

NCBI Accession: NP_036438

UniProt: Q9BWQ8