SERPINH1 Antikörper (AA 247-418)

Produktnummer ABIN3032548

Produktdetails anti-SERPINH1 Antikörper

Target: SERPINH1 (Serpin Family H Member 1 (SERPINH1))

Bindungsspezifität: AA 247-418

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SERPINH1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: Antigen affinity

Immunogen: Human partial recombinant protein (AA 247-418) was used as the immunogen for this HSP47 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: The stated application concentrations are suggested starting amounts. Titration of the HSP47 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: -20 °C

Informationen zur Lagerung: After reconstitution, the HSP47 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Details zu SERPINH1

Target: SERPINH1 (Serpin Family H Member 1 (SERPINH1))

Andere Bezeichnung: HSP47 (SERPINH1 Produkte)

Synonyme: AsTP3 antikoerper, CBP1 antikoerper, CBP2 antikoerper, HSP47 antikoerper, OI10 antikoerper, PPROM antikoerper, RA-A47 antikoerper, SERPINH2 antikoerper, gp46 antikoerper, SERPINH1 antikoerper, DKFZp468B197 antikoerper, cb216 antikoerper, hsp antikoerper, hsp47 antikoerper, id:ibd5060 antikoerper, wu:fc56b02 antikoerper, BERF-1 antikoerper, Cbp1 antikoerper, Cbp2 antikoerper, Hsp47 antikoerper, J6 antikoerper, Serpinh2 antikoerper, colligin antikoerper, astp3 antikoerper, cbp1 antikoerper, cbp2 antikoerper, pig14 antikoerper, pprom antikoerper, ra-a47 antikoerper, serpinh2 antikoerper, serpin family H member 1 antikoerper, serpin peptidase inhibitor, clade H (heat shock protein 47), member 1b antikoerper, serpin H1 antikoerper, selenoprotein K antikoerper, serine (or cysteine) peptidase inhibitor, clade H, member 1 antikoerper, serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) L homeolog antikoerper, SERPINH1 antikoerper, serpinh1b antikoerper, LOC100009353 antikoerper, Selenok antikoerper, Serpinh1 antikoerper, serpinh1.L antikoerper

Substanzklasse: Viral Protein

Hintergrund: Heat shock protein 47, also known as SERPINH1, is a serpin which serves as a human chaperone protein for collagen. It is a member of the serpin superfamily of serine proteinase inhibitors. Its expression is induced by heat shock. HSP47 localizes to the endoplasmic reticulum lumen and binds collagen, thus it is thought to be a molecular chaperone involved in the maturation of collagen molecules. Autoantibodies to this protein have been found in patients with rheumatoid arthritis. It has been found that HSP47 monitors the integrity of the triple helix of type I procollagen at the ER/cis-Golgi boundary and, when absent, the rate of transit from the ER to the Golgi is increased and the helical structure is compromised.

Gen-ID: 871