PER2 Antikörper (AA 13-330)

Produktnummer ABIN3032182

Produktdetails anti-PER2 Antikörper

Target: PER2 (Period Circadian Protein 2 (PER2))

Bindungsspezifität: AA 13-330

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PER2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: Antigen affinity

Immunogen: Human partial recombinant protein (AA 13-330) was used as the immunogen for this PER2 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: The stated application concentrations are suggested starting amounts. Titration of the PER2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: -20 °C

Informationen zur Lagerung: After reconstitution, the PER2 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Details zu PER2

Target: PER2 (Period Circadian Protein 2 (PER2))

Andere Bezeichnung: PER2 (PER2 Produkte)

Synonyme: FASPS antikoerper, FASPS1 antikoerper, mKIAA0347 antikoerper, mPer2 antikoerper, rPER2 antikoerper, gPer2 antikoerper, fj43b09 antikoerper, wu:fj43b09 antikoerper, period circadian regulator 2 antikoerper, period circadian clock 2 antikoerper, PER2 antikoerper, Per2 antikoerper, per2 antikoerper

Hintergrund: Period circadian protein homolog 2 is a member of the Period family of proteins and is expressed in a circadian pattern in the suprachiasmatic nucleus, the primary circadian pacemaker in the mammalian brain. It has been showed that PER2 can positively stimulate activity of the Bmal1-Npas2 transcription complex and, in turn, Npas2 transcriptionally regulates delta-aminolevulinate synthase. It is involved in a negative-feedback loop that attenuates estrogen stimulation and links the circadian cycle to estrogen receptor signaling. The rhythmic levels of PER2 are critical for circadian oscillations in cells and intact organisms. The protein also functions in tumor suppression by regulating DNA damage-responsive pathways.

Gen-ID: 8864