NOX1 Antikörper (AA 354-374)
-
- Target Alle NOX1 Antikörper anzeigen
- NOX1 (NADPH Oxidase 1 (NOX1))
-
Bindungsspezifität
- AA 354-374
-
Reaktivität
- Human
-
Wirt
- Kaninchen
-
Klonalität
- Polyklonal
-
Konjugat
- Dieser NOX1 Antikörper ist unkonjugiert
-
Applikation
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Aufreinigung
- Antigen affinity
- Immunogen
- Amino acids 354-374 (HIRAAGDWTENLIRAFEQQYS-human) were used as the immunogen for this NOX1 antibody.
- Isotyp
- IgG
- Top Product
- Discover our top product NOX1 Primärantikörper
-
-
- Applikationshinweise
- The stated application concentrations are suggested starting amounts. Titration of the NOX1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Buffer
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
- Lagerung
- -20 °C
- Informationen zur Lagerung
- After reconstitution, the NOX1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
-
- Target
- NOX1 (NADPH Oxidase 1 (NOX1))
- Andere Bezeichnung
- NOX1 (NOX1 Produkte)
- Synonyme
- GP91-2 antikoerper, MOX1 antikoerper, NOH-1 antikoerper, NOH1 antikoerper, NOX1a antikoerper, NOX1alpha antikoerper, Nox-1 antikoerper, Nox1 antikoerper, NADPH oxidase 1 antikoerper, NOX1 antikoerper, Nox1 antikoerper, nox1 antikoerper
- Hintergrund
- NADPH Oxidase 1, also known as NOH1, MOX1 or GP91-2, is an enzyme that in humans is encoded by the NOX1 gene. It is also a homolog of the catalytic subunit of the superoxide-generating NADPH oxidase of phagocytes, gp91phox. NOX1 is expressed in colon, prostate, uterus, and vascular smooth muscle, but not in peripheral blood leukocytes. The deduced 564-amino acid protein, which is 58 % identical to CYBB, contains 6 membrane-spanning regions, conserved flavin and pyridine nucleotide-binding sites, and histidines possibly involved in heme ligation. Overexpression of NOX1 in NIH 3T3 cells increased superoxide generation and cell growth. Cells expressing the protein had a transformed appearance, showed anchorage-independent growth, and produced tumors in athymic mice. Disruption of either Nox1 or Nox2 significantly delayed progression of motor neuron disease in these mice. However, 50 % survival rates were enhanced significantly more by Nox2 deletion than Nox1 deletion.
- UniProt
- Q9Y5S8
- Pathways
- Regulation of Systemic Arterial Blood Pressure by Hormones, Proton Transport
-