KIF2C Antikörper (AA 531-725)

Produktnummer ABIN3031553

Produktdetails anti-KIF2C Antikörper

Target: KIF2C (Kinesin Family Member 2C (KIF2C))

Bindungsspezifität: AA 531-725

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KIF2C Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: Antigen affinity

Immunogen: Human partial recombinant protein (AA 531-725) was used as the immunogen for this MCAK antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: The stated application concentrations are suggested starting amounts. Titration of the MCAK antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: -20 °C

Informationen zur Lagerung: After reconstitution, the MCAK antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Details zu KIF2C

Target: KIF2C (Kinesin Family Member 2C (KIF2C))

Andere Bezeichnung: MCAK (KIF2C Produkte)

Synonyme: kif2c antikoerper, MGC89391 antikoerper, KIF2C antikoerper, si:ch211-61f14.1 antikoerper, KNSL6 antikoerper, MCAK antikoerper, 4930402F02Rik antikoerper, ESTM5 antikoerper, Knsl6 antikoerper, X83316 antikoerper, KRP2 antikoerper, kcm1 antikoerper, mcak antikoerper, kinesin family member 2C antikoerper, kinesin family member 2C S homeolog antikoerper, KIF2C antikoerper, kif2c antikoerper, Kif2c antikoerper, kif2c.S antikoerper

Hintergrund: Kinesin-like protein, also called Mitotic centromere associated kinesin (MCAK), is a protein that in humans is encoded by the KIF2C gene. It is mapped to 1p34.1. The protein encoded by this gene is a member of kinesin-like protein family. Most proteins of this family are microtubule-dependent molecular motors that transport organelles within cells and move chromosomes during cell division. This protein acts to regulate microtubule dynamics in cells and is important for anaphase chromosome segregation and may be required to coordinate the onset of sister centromere separation. MCAK uses microtubule depolymerizing activity to correct improper microtubule attachments at kinetochores.

Gen-ID: 11004

Pathways: Microtubule Dynamics