JUP Antikörper (AA 556-745)

Produktnummer ABIN3031519

Produktdetails anti-JUP Antikörper

Target: JUP (Junction Plakoglobin (JUP))

Bindungsspezifität: AA 556-745

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser JUP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))

Aufreinigung: Antigen affinity

Immunogen: Human partial recombinant protein (AA 556-745) was used as the immunogen for this Plakoglobin antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: The stated application concentrations are suggested starting amounts. Titration of the Plakoglobin antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL,IHC (Frozen): 0.5-1 μg/mL,Immunocytochemistry: 0.5-1 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: -20 °C

Informationen zur Lagerung: After reconstitution, the Plakoglobin antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Details zu JUP

Target: JUP (Junction Plakoglobin (JUP))

Andere Bezeichnung: Plakoglobin (Gamma Catenin) (JUP Produkte)

Synonyme: ARVD12 antikoerper, CTNNG antikoerper, DP3 antikoerper, DPIII antikoerper, PDGB antikoerper, PKGB antikoerper, arvd12 antikoerper, ctnng antikoerper, dp3 antikoerper, dpiii antikoerper, pdgb antikoerper, pkgb antikoerper, plak antikoerper, D930025P04Rik antikoerper, PG antikoerper, cb80 antikoerper, danPG antikoerper, fb11b06 antikoerper, jup antikoerper, wu:fb11b06 antikoerper, junction plakoglobin antikoerper, junction plakoglobin L homeolog antikoerper, Junction plakoglobin antikoerper, junction plakoglobin a antikoerper, junction plakoglobin S homeolog antikoerper, JUP antikoerper, Jup antikoerper, jup antikoerper, jup.L antikoerper, Tsp_06656 antikoerper, plak antikoerper, jupa antikoerper, jup.S antikoerper

Hintergrund: Junction Plakoglobin (JUP), also known as< a href=../search_result.php?search_txt=gamma>gamma-catenin, is a protein that in humans is encoded by the JUP gene. It is a member of the catenin protein family and homologous to< a href=../search_result.php?search_txt=beta>< font face=symbol>b-catenin, and it is mapped to 17q21.2. This gene encodes a major cytoplasmic protein that is the only known constituent common to submembranous plaques of both desmosomes and intermediate junctions. This protein forms distinct complexes with cadherins and desmosomal cadherins. Additionally, Plakoglobin may have distinct roles in Wnt signaling and cancer via differential effects on downstream target genes.

Gen-ID: 3728

Pathways: Cell-Cell Junction Organization, Maintenance of Protein Location