IL23A Antikörper (N-Term)

Produktnummer ABIN3031472

Produktdetails anti-IL23A Antikörper

Target: IL23A (Interleukin 23, alpha subunit p19 (IL23A))

Bindungsspezifität: N-Term

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IL23A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: Antigen affinity

Immunogen: An amino acid sequence from the N-terminus of mouse IL23 p19 (DWAQCQQLSRNLCMLAWNAH) was used as the immunogen for this IL23 p19 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: The stated application concentrations are suggested starting amounts. Titration of the IL23 p19 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: -20 °C

Informationen zur Lagerung: After reconstitution, the IL23 p19 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Details zu IL23A

Target: IL23A (Interleukin 23, alpha subunit p19 (IL23A))

Andere Bezeichnung: IL23 p19 (IL23A Produkte)

Synonyme: IL-23 antikoerper, IL-23A antikoerper, IL23P19 antikoerper, P19 antikoerper, SGRF antikoerper, FIL1 antikoerper, FIL1(ZETA) antikoerper, FIL1Z antikoerper, IL-1F7 antikoerper, IL-1H antikoerper, IL-1H4 antikoerper, IL-1RP1 antikoerper, IL-37 antikoerper, IL1F7 antikoerper, IL1H4 antikoerper, IL1RP1 antikoerper, p19 antikoerper, il23p19 antikoerper, IL23 antikoerper, interleukin 23 subunit alpha antikoerper, interleukin 37 antikoerper, interleukin 23, alpha subunit p19 antikoerper, IL23A antikoerper, IL37 antikoerper, Il23a antikoerper

Hintergrund: Interleukin-23 is a heterodimeric cytokine consisting of two subunits, one called p40, which is shared with another cytokine, IL-12, and another called p19 (the IL-23 alpha subunit). The International Radiation Hybrid Mapping Consortium mapped the IL-23 gene to chromosome 12. The cytokine is an important part of the inflammatory response against infection. It promotes upregulation of the matrix metalloprotease MMP9, increases angiogenesis and reduces CD8+ T-cell infiltration.

UniProt: Q9EQ14

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation