GATA2 Antikörper (N-Term)

Produktnummer ABIN3031027

Produktdetails anti-GATA2 Antikörper

Target: GATA2 (GATA Binding Protein 2 (GATA2))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GATA2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: Antigen affinity

Immunogen: An amino acid sequence from the N-terminus of human GATA2 (DVFFNHLDSQGNPYY) was used as the immunogen for this GATA2 antibody (100% homologous in human, mouse and rat).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: The stated application concentrations are suggested starting amounts. Titration of the GATA2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: -20 °C

Informationen zur Lagerung: After reconstitution, the GATA2 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Details zu GATA2

Target: GATA2 (GATA Binding Protein 2 (GATA2))

Andere Bezeichnung: GATA2 (GATA2 Produkte)

Synonyme: DCML antikoerper, MONOMAC antikoerper, NFE1B antikoerper, Gata-2 antikoerper, xgata-2 antikoerper, xgata2 antikoerper, GATA-2 antikoerper, NF-E1b antikoerper, GATA2 antikoerper, Gata2 antikoerper, gata2 antikoerper, zg2 antikoerper, zgc:91840 antikoerper, GATA binding protein 2 antikoerper, GATA binding protein 2 L homeolog antikoerper, amidase antikoerper, glutamyl/aspartyl-tRNA(Gln/Asp) amidotransferasesubunit A antikoerper, hypothetical protein antikoerper, glutamyl-tRNA(Gln) amidotransferase, subunit GatA (Glu-ADT subunit A) antikoerper, GATA2 transcription factor antikoerper, putative gata binding factor antikoerper, GATA binding protein 2a antikoerper, GATA binding protein 2b antikoerper, GATA2 antikoerper, Gata2 antikoerper, gata2.L antikoerper, RR_RS20245 antikoerper, gatA2 antikoerper, Smp_018590 antikoerper, gata2a antikoerper, gata2b antikoerper

Hintergrund: The GATA family of transcription factors, which contain zinc fingers in their DNA binding domain, have emerged as candidate regulators of gene expression in hematopoietic cells. Ciciotte et al.(1997) mapped the mouse GATA2 gene to chromosome 6 by study of DNA from an interspecific backcross panel. They pointed out that the human gene had been mapped to chromosome 3 by Dorfman et al.(1992) using DNA from a panel of 12 rodent/human hybrids containing various human chromosomes and applying Southern blot analysis. By exon trapping using a PAC contig spanning a breakpoint region associated with myeloid leukemia, Wieser et al.(2000) mapped the GATA2 gene to chromosome 3q21. GATA2 is transcribed from telomere to centromere. GATA2 is expressed in hematopoietic progenitors, including early erythroid cells, mast cells, and megakaryocytes, and also in nonhematopoietic embryonic stem cells.

UniProt: P23769

Pathways: Stem Cell Maintenance