COL4A1 Antikörper (AA 1445-1669)

Produktnummer ABIN3030553

Produktdetails anti-COL4A1 Antikörper

Target: COL4A1 (Collagen, Type IV, alpha 1 (COL4A1))

Bindungsspezifität: AA 1445-1669

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser COL4A1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: Antigen affinity

Immunogen: Human partial recombinant protein (AA 1445-1669) was used as the immunogen for this Collagen IV antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: The stated application concentrations are suggested starting amounts. Titration of the Collagen IV antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: -20 °C

Informationen zur Lagerung: After reconstitution, the Collagen IV antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Details zu COL4A1

Target: COL4A1 (Collagen, Type IV, alpha 1 (COL4A1))

Andere Bezeichnung: Collagen IV / COL4A1 (COL4A1 Produkte)

Synonyme: col4a1 antikoerper, wu:fc02g11 antikoerper, HANAC antikoerper, ICH antikoerper, POREN1 antikoerper, arresten antikoerper, Bru antikoerper, Col4a-1 antikoerper, Del(8)44H antikoerper, Raw antikoerper, Svc antikoerper, collagen, type IV, alpha 5 (Alport syndrome) antikoerper, collagen type IV alpha 1 chain antikoerper, collagen, type IV, alpha 1 antikoerper, col4a5 antikoerper, COL4A1 antikoerper, Col4a1 antikoerper

Hintergrund: COL4A1, also known as ICH or Collagen alpha-1(IV), is a protein that in humans is encoded by the COL4A1 gene. It is mapped to 13q34. This gene encodes the major type IV alpha collagen chain of basement membranes. Like the other members of the type IV collagen gene family, this gene is organized in a head-to-head conformation with another type IV collagen gene so that each gene pair shares a common promoter. COL4A1 binds to alpha-1/beta-1 integrin and inhibits migration, proliferation, and tube formation by endothelial cells. It is also a potential therapeutic candidate for targeting tumor angiogenesis.

Gen-ID: 1282

Pathways: Skeletal Muscle Fiber Development, Growth Factor Binding