CXCR6 Antikörper (C-Term)

Produktnummer ABIN3030518

Produktdetails anti-CXCR6 Antikörper

Target: CXCR6 (Chemokine (C-X-C Motif) Receptor 6 (CXCR6))

Bindungsspezifität: C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CXCR6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: Antigen affinity

Immunogen: An amino acid sequence from the C-terminus of human Chemokine CXC Motif Receptor 6 (EDNSKTFSASHNVEATSMFQL) was used as the immunogen for this CXCR6 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: The stated application concentrations are suggested starting amounts. Titration of the CXCR6 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: -20 °C

Informationen zur Lagerung: After reconstitution, the CXCR6 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Details zu CXCR6

Target: CXCR6 (Chemokine (C-X-C Motif) Receptor 6 (CXCR6))

Andere Bezeichnung: CXCR6 (CXCR6 Produkte)

Synonyme: BONZO antikoerper, CD186 antikoerper, STRL33 antikoerper, TYMSTR antikoerper, BB217514 antikoerper, C-X-C motif chemokine receptor 6 antikoerper, chemokine (C-X-C motif) receptor 6 L homeolog antikoerper, chemokine (C-X-C motif) receptor 6 antikoerper, CXCR6 antikoerper, cxcr6.L antikoerper, Cxcr6 antikoerper

Hintergrund: Chemokine CXC Motif Receptor 6, also known as STRL33 and Bonzo, is a protein that in humans is encoded by the CXCR6 gene. By Southern blot analysis of genomic DNA and somatic cell hybrid analysis, Liao et al.(1997) mapped the single-copy gene to chromosome 3. Matloubian et al.(2000) found that human and mouse cells expressing the protein showed a strong chemotactic response to CXCL16 but not to other chemokines. The authors concluded that CXCL16 and CXCR6 most likely function in interactions between dendritic cells and T cells and in regulating T-cell migration in the splenic red pulp. Kim et al.(2001) concluded that the proteinb may be important in the trafficking of effector T cells mediating type-1 inflammation.

UniProt: O00574