CCR6 Antikörper (C-Term)

Produktnummer ABIN3030496

Produktdetails anti-CCR6 Antikörper

Target: CCR6 (Chemokine (C-C Motif) Receptor 6 (CCR6))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CCR6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: Antigen affinity

Immunogen: An amino acid sequence from the C-terminus of human CCR6 (RQTSETADNDNASSFTM) was used as the immunogen for this CCR6 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: The stated application concentrations are suggested starting amounts. Titration of the CCR6 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: -20 °C

Informationen zur Lagerung: After reconstitution, the CCR6 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Details zu CCR6

Target: CCR6 (Chemokine (C-C Motif) Receptor 6 (CCR6))

Andere Bezeichnung: CCR6 (CCR6 Produkte)

Synonyme: BN-1 antikoerper, C-C CKR-6 antikoerper, CC-CKR-6 antikoerper, CCR-6 antikoerper, CD196 antikoerper, CKR-L3 antikoerper, CKRL3 antikoerper, CMKBR6 antikoerper, DCR2 antikoerper, DRY6 antikoerper, GPR29 antikoerper, GPRCY4 antikoerper, STRL22 antikoerper, Cmkbr6 antikoerper, KY411 antikoerper, C-C motif chemokine receptor 6 antikoerper, chemokine (C-C motif) receptor 6 antikoerper, CCR6 antikoerper, Ccr6 antikoerper

Hintergrund: CCR6, also termed CKRL3, encodes a 369-amino acid polypeptide with greatest similarity to the family of alpha-chemokine-binding receptors. Unlike most chemokine receptor genes, it is encoded by more than 1 exon. Weakly expressed as a 4-kb transcript in spleen, lymph nodes, peripheral blood lymphocytes and appendix, CCR6 gene is located at 6q27. As the receptor for MIP-3-alpha, its activation leads to phospholipase C-dependent intracellular Ca(2+) mobilization. Additionally, CCR6 are markedly upregulated in psoriasis.

UniProt: P51684

Pathways: cAMP Metabolic Process