ARG2 Antikörper (N-Term)

Produktnummer ABIN3030019

Produktdetails anti-ARG2 Antikörper

Target: ARG2 (Arginase, Type II (ARG2))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ARG2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: Antigen affinity

Immunogen: An amino acid sequence from the N-terminus of human Arginase II (DFGDLSFTPVPKDDLYNNL) was used as the immunogen for this Arg2 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: The stated application concentrations are suggested starting amounts. Titration of the Arg2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: -20 °C

Informationen zur Lagerung: After reconstitution, the Arg2 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Details zu ARG2

Target: ARG2 (Arginase, Type II (ARG2))

Andere Bezeichnung: Arg2 (ARG2 Produkte)

Synonyme: AII antikoerper, AU022422 antikoerper, zgc:65793 antikoerper, zgc:85630 antikoerper, wu:fb67g02 antikoerper, ARG2 antikoerper, LeARG2 antikoerper, arg1 antikoerper, arg3 antikoerper, arg2 antikoerper, arg2-c antikoerper, arg2-b antikoerper, arginase 2 antikoerper, arginase type II antikoerper, arginase 2 L homeolog antikoerper, arginase 2 S homeolog antikoerper, ARG2 antikoerper, Arg2 antikoerper, arg2 antikoerper, arg2.L antikoerper, arg2.S antikoerper

Hintergrund: Arginase, type II encodes a 355-amino acid polypeptide. Using Northern blotting and RT-PCR, Vockley et al.(1996) found that ARG2 is expressed as a 1.5-kb mRNA in a wide variety of tissues, with highest levels of expression in prostate, brain, and kidney. ARG2 may be inducible and may be essential in the regulation of nitric oxide synthesis by modulating local arginine concentrations. Gotoh et al.(1996) showed that ARG2 mRNA and nitric oxide synthase (NOS) mRNA were coinduced by lipopolysaccharide in a macrophage-like cell line. Arginase II has been implicated in the regulation of the arginine/ornithine concentrations in the cell. The mitochondrial location of the protein and its coinduction with ornithine aminotransferase and involvement with proline biosynthesis in lactating rat mammary gland had led to the inference that it is involved in biosynthetic functions, as opposed to the metabolic ones of the urea cycle.

UniProt: P78540