ALOX5 Antikörper (AA 120-483)

Produktnummer ABIN3030014

Produktdetails anti-ALOX5 Antikörper

Target: ALOX5 (Arachidonate 5-Lipoxygenase (ALOX5))

Bindungsspezifität: AA 120-483

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ALOX5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: Antigen affinity

Immunogen: Human partial recombinant protein (AA 120-483) was used as the immunogen for this 5-Lipoxygenase antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: The stated application concentrations are suggested starting amounts. Titration of the 5-Lipoxygenase antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: -20 °C

Informationen zur Lagerung: After reconstitution, the 5-Lipoxygenase antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Details zu ALOX5

Target: ALOX5 (Arachidonate 5-Lipoxygenase (ALOX5))

Andere Bezeichnung: 5-Lipoxygenase (ALOX5 Produkte)

Synonyme: 5-LO antikoerper, 5-LOX antikoerper, 5LPG antikoerper, LOG5 antikoerper, 5LO antikoerper, 5LX antikoerper, AI850497 antikoerper, F730011J02 antikoerper, LOX5A antikoerper, si:dkey-194n13.2 antikoerper, lox5 antikoerper, arachidonate 5-lipoxygenase antikoerper, arachidonate 5-lipoxygenase a antikoerper, Arachidonate 5-lipoxygenase antikoerper, ALOX5 antikoerper, Alox5 antikoerper, alox5a antikoerper, AFUA_4G02770 antikoerper, AOR_1_1362014 antikoerper, lox5 antikoerper

Hintergrund: Arachidonate 5-lipoxygenase, also known as 5-LOX or 5-LO, is an enzyme that in humans is encoded by the ALOX5 gene. It is a member of the lipoxygenase family of enzymes. It is mapped to 10q11.21. ALOX5 plays a dual role in the synthesis of leukotrienes from arachidonic acid. Its position within the nucleus of resting cells determines the capacity to generate LTB4 upon subsequent activation. It is involved in lung vascular tone regulation and in the development of chronic pulmonary hypertension in hypoxic rodent models. ALOX5 also transforms EFAs into leukotrienes and is a current target for pharmaceutical intervention in a number of diseases.

Gen-ID: 240