ADRA2A Antikörper (C-Term)

Produktnummer ABIN3029880

Produktdetails anti-ADRA2A Antikörper

Target: ADRA2A (Alpha-2A Adrenergic Receptor (ADRA2A))

Bindungsspezifität: C-Term

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ADRA2A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: Antigen affinity

Immunogen: An amino acid sequence from the C-terminus of human alpha 2a Adrenergic Receptor (FGYCNSSLNPVIYTIFNH) was used as the immunogen for this alpha 2a Adrenergic Receptor antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: The stated application concentrations are suggested starting amounts. Titration of the alpha 2a Adrenergic Receptor antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: -20 °C

Informationen zur Lagerung: After reconstitution, the alpha 2a Adrenergic Receptor antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Details zu ADRA2A

Target: ADRA2A (Alpha-2A Adrenergic Receptor (ADRA2A))

Andere Bezeichnung: alpha 2a Adrenergic Receptor (ADRA2A Produkte)

Synonyme: ADRA2A antikoerper, AW122659 antikoerper, Adra-2 antikoerper, Adra-2a antikoerper, alpha(2A)AR antikoerper, alpha2-C10 antikoerper, alpha2A antikoerper, alpha2A-AR antikoerper, ADRA2 antikoerper, ADRA2R antikoerper, ADRAR antikoerper, ALPHA2AAR antikoerper, ZNF32 antikoerper, CA2-47 antikoerper, RATRG20 antikoerper, RG20 antikoerper, PORA2AR antikoerper, adrenoceptor alpha 2A antikoerper, alpha-2A adrenergic receptor-like antikoerper, adrenergic receptor, alpha 2a antikoerper, adra2a antikoerper, ADRA2A antikoerper, LOC100414445 antikoerper, Adra2a antikoerper

Hintergrund: Alpha-2-adrenergic receptor(ADRA2), also known as platelet type adrenoceptor alpha-2A ,is a member of G protein-coupled receptor superfamily. This gene, which can identify a DraI RFLP of the ADRAR gene, mapped to 10q23-q25, is found in the distal region of mouse chromosome 19 and abundantly expressed in giant cell. ADRA2 acts a critical role in regulating neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system. It has 3 highly homologous subtypes: ADRA2A, ADRA2B and ADRA2C. Studies in mouse suggested that both the ADRA2A and ADRA2C subtypes are required for normal presynaptic control of transmitter release from sympathetic nerves in the heart and from central noradrenergic neurons. ADRA2A receptors inhibited transmitter release at high stimulation frequencies, whereas the ADRA2C subtype modulated neurotransmission at lower levels of nerve activity.

UniProt: P08913

Pathways: EGFR Signaling Pathway, Negative Regulation of Hormone Secretion, Carbohydrate Homeostasis, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling, Negative Regulation of Transporter Activity