ADAMTS1 Antikörper (AA 956-968)

Produktnummer ABIN3029863

Produktdetails anti-ADAMTS1 Antikörper

Target: ADAMTS1 (ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 1 (ADAMTS1))

Bindungsspezifität: AA 956-968

Reaktivität: Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ADAMTS1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: Antigen affinity

Immunogen: Amino acids 956-968 (KHYIDFCTLTQCS-mouse) were used as the immunogen for this ADAMTS1 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: The stated application concentrations are suggested starting amounts. Titration of the ADAMTS1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: -20 °C

Informationen zur Lagerung: After reconstitution, the ADAMTS1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Details zu ADAMTS1

Target: ADAMTS1 (ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 1 (ADAMTS1))

Andere Bezeichnung: ADAMTS1 (ADAMTS1 Produkte)

Synonyme: c3-c5 antikoerper, meth1 antikoerper, xadamts1 antikoerper, C3-C5 antikoerper, METH1 antikoerper, ADAM-TS1 antikoerper, ADAMTS antikoerper, ADAMTS-1 antikoerper, METH-1 antikoerper, adamts1 antikoerper, ADAM metallopeptidase with thrombospondin type 1 motif 1 antikoerper, ADAM metallopeptidase with thrombospondin type 1 motif, 1 antikoerper, a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 1 antikoerper, ADAM metallopeptidase with thrombospondin type 1 motif 1 L homeolog antikoerper, ADAMTS1 antikoerper, adamts1 antikoerper, Adamts1 antikoerper, adamts1.L antikoerper

Hintergrund: A Disintegrin-Like and Metalloproteinase with Thrombospondin Type 1 Motif, 1, also known as METH1, is an enzyme that in humans is encoded by the ADAMTS1 gene. ADAMTS is a family of proteins believed to be anchored to the extracellular matrix(ECM) through interactions with aggregan or other matrix components by one or more thrombospondin type 1 motifs. Scott(2000) mapped the gene to 21q21.2 based on sequence similarity between the ADAMTS1 sequence and a chromosome 21q21.2 clone. Kuno et al.(1997) found that mouse Adamts1 expression could be induced in vitro in colon adenocarcinoma cells by stimulation with the inflammatory cytokine interleukin 1-alpha, or in vivo in kidney and heart by intravenous administration of lipopolysaccharide. Vazquez et al.(1999) determined that ADAMTS1 disrupts angiogenesis in vivo and in vitro more efficiently than ADAMTS8, THBS1, or endostatin.

UniProt: P97857

Pathways: SARS-CoV-2 Protein Interaktom