ODC1 Antikörper

Produktnummer ABIN3026476

Produktdetails anti-ODC1 Antikörper

Target: ODC1 (Ornithine Decarboxylase 1 (ODC1))

Reaktivität: Human, Ratte

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser ODC1 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktmerkmale: This antibody recognizes a 53 kDa protein, identified as the Ornithine Decarboxylase. ODC-1 is the initial and rate-limiting enzyme in the biosynthetic pathway of polyamines and is involved in the conversion of ornithine to putrescine. The biological activity of ODC-1 is rapidly induced in response to virtually all agents known to promote cell proliferation including hormones, drugs, growth factors, mitogens, and tumor promoters. Reportedly, ODC-1 mRNA levels are elevated in lung carcinomas as well as in colon adenomas and carcinomas. Activity in colorectal carcinomas is greater than those in adenomas and normal mucosa.

Aufreinigung: Protein G affinity chromatography

Immunogen: Recombinant human ODC-1 protein was used as the immunogen for this antibody.

Klon: ODC1-485

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise: The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the antibody to be titered up or down for optimal performance.

1. Staining of formalin-fixed tissues requires boiling tissue sections in 10  mM citrate buffer,  pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes.
2. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.\. Prediluted IHC only format : incubate for 30 min at RT (2)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Prediluted in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide, *For IHC use only*

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store the ODC-1 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).

Details zu ODC1

Target: ODC1 (Ornithine Decarboxylase 1 (ODC1))

Andere Bezeichnung: ODC-1 / Ornithine Decarboxylase 1 (ODC1 Produkte)

Synonyme: CG8721 antikoerper, Dmel\\CG8721 antikoerper, dodc1 antikoerper, odc antikoerper, fc54f04 antikoerper, fi06d08 antikoerper, CHUNP6922 antikoerper, wu:fc54f04 antikoerper, wu:fi06d08 antikoerper, odc2 antikoerper, xODC1 antikoerper, xodc2 antikoerper, DDBDRAFT_0204020 antikoerper, DDBDRAFT_0237755 antikoerper, DDB_0204020 antikoerper, DDB_0237755 antikoerper, ODC antikoerper, odc1 antikoerper, ODC1 antikoerper, Odc antikoerper, odc1-a antikoerper, Ornithine decarboxylase 1 antikoerper, ornithine decarboxylase 1 antikoerper, ornithine decarboxylase antikoerper, diaminopimelate decarboxylase antikoerper, Orn/DAP/Arg decarboxylase 2 domain-containing protein antikoerper, Diaminopimelate decarboxylase antikoerper, Ornithine decarboxylase antikoerper, ornithine decarboxylase 1 L homeolog antikoerper, ornithine decarboxylase, structural 1 antikoerper, Odc1 antikoerper, odc1 antikoerper, ODC1 antikoerper, odc antikoerper, RR_RS04895 antikoerper, ASA_RS06380 antikoerper, LOC100232922 antikoerper, odc1.L antikoerper, odc-1 antikoerper

Hintergrund: This antibody recognizes a 53  kDa protein, identified as the Ornithine Decarboxylase. ODC-1 is the initial and rate-limiting enzyme in the biosynthetic pathway of polyamines and is involved in the conversion of ornithine to putrescine. The biological activity of ODC-1 is rapidly induced in response to virtually all agents known to promote cell proliferation including hormones, drugs, growth factors, mitogens, and tumor promoters. Reportedly, ODC-1 mRNA levels are elevated in lung carcinomas as well as in colon adenomas and carcinomas. Activity in colorectal carcinomas is greater than those in adenomas and normal mucosa.

Gen-ID: 4953