ODC1 Antikörper

Produktnummer ABIN3026475

Produktdetails anti-ODC1 Antikörper

Target: ODC1 (Ornithine Decarboxylase 1 (ODC1))

Reaktivität: Human, Ratte

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser ODC1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktmerkmale: This antibody recognizes a 53 kDa protein, identified as the Ornithine Decarboxylase. ODC-1 is the initial and rate-limiting enzyme in the biosynthetic pathway of polyamines and is involved in the conversion of ornithine to putrescine. The biological activity of ODC-1 is rapidly induced in response to virtually all agents known to promote cell proliferation including hormones, drugs, growth factors, mitogens, and tumor promoters. Reportedly, ODC-1 mRNA levels are elevated in lung carcinomas as well as in colon adenomas and carcinomas. Activity in colorectal carcinomas is greater than those in adenomas and normal mucosa.

Aufreinigung: Protein G affinity chromatography

Immunogen: Recombinant human ODC-1 protein was used as the immunogen for this antibody.

Klon: ODC1-485

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise: The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the antibody to be titered up or down for optimal performance.

1. Staining of formalin-fixed tissues requires boiling tissue sections in 10  mM citrate buffer,  pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes.
2. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.\. FACS: 0.5-1 μg/million cells,IF: 0.5-1 μg/mL,WB: 0.5-1 μg/mL,IHC (FFPE): 0.5-1 μg/mL for 30 minutes at RT (1),Prediluted format : incubate for 30 min at RT (2)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store the ODC-1 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).

Details zu ODC1

Target: ODC1 (Ornithine Decarboxylase 1 (ODC1))

Andere Bezeichnung: ODC-1 / Ornithine Decarboxylase 1 (ODC1 Produkte)

Synonyme: CG8721 antikoerper, Dmel\\CG8721 antikoerper, dodc1 antikoerper, odc antikoerper, fc54f04 antikoerper, fi06d08 antikoerper, CHUNP6922 antikoerper, wu:fc54f04 antikoerper, wu:fi06d08 antikoerper, odc2 antikoerper, xODC1 antikoerper, xodc2 antikoerper, DDBDRAFT_0204020 antikoerper, DDBDRAFT_0237755 antikoerper, DDB_0204020 antikoerper, DDB_0237755 antikoerper, ODC antikoerper, odc1 antikoerper, ODC1 antikoerper, Odc antikoerper, odc1-a antikoerper, Ornithine decarboxylase 1 antikoerper, ornithine decarboxylase 1 antikoerper, ornithine decarboxylase antikoerper, diaminopimelate decarboxylase antikoerper, Orn/DAP/Arg decarboxylase 2 domain-containing protein antikoerper, Diaminopimelate decarboxylase antikoerper, Ornithine decarboxylase antikoerper, ornithine decarboxylase 1 L homeolog antikoerper, ornithine decarboxylase, structural 1 antikoerper, Odc1 antikoerper, odc1 antikoerper, ODC1 antikoerper, odc antikoerper, RR_RS04895 antikoerper, ASA_RS06380 antikoerper, LOC100232922 antikoerper, odc1.L antikoerper, odc-1 antikoerper

Hintergrund: This antibody recognizes a 53  kDa protein, identified as the Ornithine Decarboxylase. ODC-1 is the initial and rate-limiting enzyme in the biosynthetic pathway of polyamines and is involved in the conversion of ornithine to putrescine. The biological activity of ODC-1 is rapidly induced in response to virtually all agents known to promote cell proliferation including hormones, drugs, growth factors, mitogens, and tumor promoters. Reportedly, ODC-1 mRNA levels are elevated in lung carcinomas as well as in colon adenomas and carcinomas. Activity in colorectal carcinomas is greater than those in adenomas and normal mucosa.

Gen-ID: 4953