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CD28 Antikörper

CD28 Reaktivität: Human, Maus, Rind (Kuh), Schwein, Schaf FACS, IF, Func Wirt: Maus Monoclonal 204-12 unconjugated
Produktnummer ABIN3025652
  • Target Alle CD28 Antikörper anzeigen
    CD28
    Reaktivität
    • 182
    • 130
    • 60
    • 38
    • 21
    • 20
    • 12
    • 12
    • 7
    • 7
    • 6
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Rind (Kuh), Schwein, Schaf
    Wirt
    • 143
    • 78
    • 29
    • 18
    • 8
    • 3
    • 2
    • 1
    Maus
    Klonalität
    • 202
    • 74
    • 3
    Monoklonal
    Konjugat
    • 95
    • 30
    • 28
    • 20
    • 15
    • 7
    • 7
    • 6
    • 6
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CD28 Antikörper ist unkonjugiert
    Applikation
    • 206
    • 95
    • 51
    • 49
    • 40
    • 30
    • 30
    • 26
    • 21
    • 17
    • 13
    • 7
    • 7
    • 6
    • 6
    • 5
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Immunofluorescence (IF), Functional Studies (Func)
    Aufreinigung
    Protein G affinity chromatography
    Immunogen
    Stimulated human leukocytes were used as the immunogen for the CD28 antibody.
    Klon
    204-12
    Isotyp
    IgG2a kappa
    Top Product
    Discover our top product CD28 Primärantikörper
  • Applikationshinweise
    Optimal dilution of the CD28 antibody should be determined by the researcher.\. Flow Cytometry: 0.5-1 μg/million cells in 0.1ml,Immunofluorescence: 0.5-1 μg/mL,Functional Activity (Order SAF formulation)
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    0.2 mg/mL
    Buffer
    0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store the CD28 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
  • Target
    CD28
    Andere Bezeichnung
    CD28 (CD28 Produkte)
    Synonyme
    Tp44 antikoerper, CD28RNA antikoerper, cd28 antikoerper, CD28 molecule antikoerper, CD28 antigen antikoerper, Cd28 molecule antikoerper, CD28 molecule L homeolog antikoerper, CD28 antikoerper, Cd28 antikoerper, cd28.L antikoerper
    Hintergrund
    Recognizes a glycoprotein of 44-88  kDa, which is identified as CD28. It is the critical T-cell co-stimulatory receptor which provides to the cell the important second activation signal by binding CD80 and CD86 that are expressed by antigen presenting cells. Besides its co-stimulation role, CD28 functions in preventing T-cells from anergic hyporesponsive state or from undergoing premature apoptotic cell death. CD28 is also expressed on human fetal NK cells and some NK cell lines, whereas on murine NK cells the CD28 expression is much broader.
    Pathways
    T-Zell Rezeptor Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
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