ODC1 Antikörper

Produktnummer ABIN3025558

Produktdetails anti-ODC1 Antikörper

Target: ODC1 (Ornithine Decarboxylase 1 (ODC1))

Reaktivität: Human, Ratte

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser ODC1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: Protein G affinity chromatography

Immunogen: Recombinant human protein was used as the immunogen for the ODC antibody.

Klon: ODC1-486

Isotyp: IgG2a kappa

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the ODC antibody should be determined by the researcher.

1. Staining of formalin-fixed tissues requires boiling tissue sections in 10  mM Citrate buffer,  pH 6.0, for 10-20 min followed by cooling at RT for 20 min
2. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.\. Flow Cytometry: 0.5-1 μg/million cells in 0.1ml,Immunofluorescence: 0.5-1 μg/mL,Western blot: 0.5-1 μg/mL,Immunohistochemistry (FFPE): 0.25-0.5 μg/mL for 30 min at RT (1),Prediluted format: incubate for 30 min at RT (2)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store the ODC antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).

Details zu ODC1

Target: ODC1 (Ornithine Decarboxylase 1 (ODC1))

Andere Bezeichnung: ODC-1 / Ornithine Decarboxylase 1 (ODC1 Produkte)

Synonyme: CG8721 antikoerper, Dmel\\CG8721 antikoerper, dodc1 antikoerper, odc antikoerper, fc54f04 antikoerper, fi06d08 antikoerper, CHUNP6922 antikoerper, wu:fc54f04 antikoerper, wu:fi06d08 antikoerper, odc2 antikoerper, xODC1 antikoerper, xodc2 antikoerper, DDBDRAFT_0204020 antikoerper, DDBDRAFT_0237755 antikoerper, DDB_0204020 antikoerper, DDB_0237755 antikoerper, ODC antikoerper, odc1 antikoerper, ODC1 antikoerper, Odc antikoerper, odc1-a antikoerper, Ornithine decarboxylase 1 antikoerper, ornithine decarboxylase 1 antikoerper, ornithine decarboxylase antikoerper, diaminopimelate decarboxylase antikoerper, Orn/DAP/Arg decarboxylase 2 domain-containing protein antikoerper, Diaminopimelate decarboxylase antikoerper, Ornithine decarboxylase antikoerper, ornithine decarboxylase 1 L homeolog antikoerper, ornithine decarboxylase, structural 1 antikoerper, Odc1 antikoerper, odc1 antikoerper, ODC1 antikoerper, odc antikoerper, RR_RS04895 antikoerper, ASA_RS06380 antikoerper, LOC100232922 antikoerper, odc1.L antikoerper, odc-1 antikoerper

Hintergrund: Recognizes a 53  kDa protein, identified as the Ornithine Decarboxylase (ODC-1). ODC is the initial and rate-limiting enzyme in the biosynthetic pathway of polyamines and is involved in the conversion of ornithine to putrescine. The biological activity of ODC-1 is rapidly induced in response to virtually all agents known to promote cell proliferation including hormones, drugs, growth factors, mitogens, and tumor promoters. Reportedly, ODC mRNA levels are elevated in lung carcinomas as well as in colon adenomas and carcinomas. ODC activity in colorectal carcinomas is greater than those in adenomas and normal mucosa.