OTUD5 Antikörper (C-Term)

Produktnummer ABIN3025356

Produktdetails anti-OTUD5 Antikörper

Target: OTUD5 (OTU Domain Containing 5 (OTUD5))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser OTUD5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: Protein A affinity chromatography

Immunogen: A recombinant protein fragment from the C-terminal region of human OTUD5 was used as the immunogen for this antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Provided assay concentrations are suggestions only, antibody titration may be required for optimal results.\. Western blot: 2-5 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: 0.5 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Details zu OTUD5

Target: OTUD5 (OTU Domain Containing 5 (OTUD5))

Andere Bezeichnung: OTUD5 (OTUD5 Produkte)

Synonyme: DUBA antikoerper, AA407879 antikoerper, AI553596 antikoerper, BB114028 antikoerper, DXImx46e antikoerper, Sfc7 antikoerper, otud5 antikoerper, si:bz30i22.1 antikoerper, si:rp71-30i22.1 antikoerper, zgc:154072 antikoerper, wu:fi28a06 antikoerper, zgc:100839 antikoerper, OTU deubiquitinase 5 antikoerper, OTU domain containing 5 antikoerper, OTU deubiquitinase 5a antikoerper, OTU deubiquitinase 5 S homeolog antikoerper, OTU deubiquitinase 5 L homeolog antikoerper, OTU deubiquitinase 5b antikoerper, OTUD5 antikoerper, Otud5 antikoerper, otud5a antikoerper, otud5.S antikoerper, otud5.L antikoerper, otud5b antikoerper

Hintergrund: OTUD5 (ovarian tumor domain-containing 5), also called DUBA (Deubiquitinating enzyme A), is a product of the OTUD5 gene, and a suppressor of the innate immune response via its deubiquitinating activity. The Innate immune systems provide immediate but short-lived defense against infection identified by PRRs, or pattern recognition receptors. OTUD5 cleaves the lysine-63-linked polyubiquitin chains of TRAF3, causing it to dissociate from TBK1, thereby failing to stimulate IFN type 1 production and leading to a suppressed innate immune response.

Gen-ID: 55593