Oxytocin Receptor Antikörper (C-Term)

Produktnummer ABIN302439

Produktdetails anti-Oxytocin Receptor Antikörper

Target: Oxytocin Receptor (OXTR)

Bindungsspezifität: C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Oxytocin Receptor Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität: This antibody detects Oxytocin Receptor (OXTR), C-terminal cytoplasmic domain.

Aufreinigung: Immunoaffinity Chromatography.

Immunogen: Synthetic peptide -KLH conjugated corresponding to C-terminal cytoplasmic domain of Human Oxytocin Receptor (OXTR).

Anwendungsinformationen

Applikationshinweise: Immunohistochemistry on Paraffin Sections (40 μg/mL). Antigen retrieval: Steam slides in 0.01M sodium citrate buffer, pH 6.0, at 99-100 °C for 20 min. Remove from heat and let stand at room temperature in buffer for 20 min. Rinse in 1xTBS with Tween (TBST) for 1 min. at room temperature.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Phosphate buffered saline containing 0.09 % Sodium Azide as preservative.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C to -70 °C for longer.

Details zu Oxytocin Receptor

Target: Oxytocin Receptor (OXTR)

Andere Bezeichnung: Oxytocin Receptor / OXTR (OXTR Produkte)

Synonyme: OXTR antikoerper, OT-R antikoerper, OTR antikoerper, OTR1 antikoerper, oxytocin receptor antikoerper, OXTR antikoerper, Oxtr antikoerper

Hintergrund: The oxytocin receptor belongs to the vasopressin/oxytocin family of GPCRs because it binds similar cyclic nonapeptide hormones. The oxytocin receptor functions primarily during labor and lactation. There is a dramatic increase in the number of oxytocin receptors just before the onset of labor causing the uterine muscles to become exceedingly sensitive to oxytocin. The activated oxytocin receptor causes an inward membrane current that results in smooth muscle contraction during labor and milk ejection during lactation. This receptor also plays a role in natriuresis, kaliuresis and may have an antistress effect.Synonyms: OT-R

Gen-ID: 5021

NCBI Accession: NP_000907

UniProt: P30559

Pathways: Myometrial Relaxation and Contraction, Feeding Behaviour