DRAM Antikörper (N-Term)

Produktnummer ABIN3024191

Produktdetails anti-DRAM Antikörper

Target: DRAM (DRAM1) (DNA-Damage Regulated Autophagy Modulator 1 (DRAM1))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DRAM Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: Protein A affinity chromatography

Immunogen: A recombinant protein fragment from the N-terminal region of human DRAM was used as the immunogen for this antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Provided assay concentrations are suggestions only, antibody titration may be required for optimal results.\. Western blot: 4-8 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: 0.5 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the DRAM antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Details zu DRAM

Target: DRAM (DRAM1) (DNA-Damage Regulated Autophagy Modulator 1 (DRAM1))

Andere Bezeichnung: DRAM (DRAM1 Produkte)

Synonyme: DRAM1 antikoerper, DRAM antikoerper, 1200002N14Rik antikoerper, Dram antikoerper, dram antikoerper, DNA damage regulated autophagy modulator 1 antikoerper, DNA-damage regulated autophagy modulator 1 antikoerper, DNA damage regulated autophagy modulator 1 L homeolog antikoerper, DRAM1 antikoerper, Dram1 antikoerper, dram1.L antikoerper

Hintergrund: Autophagy is the mechanism by which lysosomes degrade unneeded or dysfunctional cellular components. p53 is a tumor suppressor protein that modulates autophagy and apoptosis. DRAM, or damage regulated autophagy modulator, is a lysosomal protein and effector of p53-mediated cell death. Many tumors show decreased DRAM expression and siRNA knockdown resulted in reduced cell death (Crighton et al, 2006).

Gen-ID: 55332