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CD1a Antikörper

CD1a Reaktivität: Human IHC (p) Wirt: Maus Monoclonal O10-C1A-711 unconjugated
Produktnummer ABIN3024182
  • Target Alle CD1a Antikörper anzeigen
    CD1a
    Reaktivität
    • 168
    • 23
    • 7
    • 5
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 111
    • 61
    Maus
    Klonalität
    • 130
    • 41
    • 1
    Monoklonal
    Konjugat
    • 68
    • 12
    • 12
    • 9
    • 8
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CD1a Antikörper ist unkonjugiert
    Applikation
    • 105
    • 60
    • 42
    • 42
    • 31
    • 28
    • 10
    • 9
    • 5
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Aufreinigung
    Protein G affinity chromatography
    Immunogen
    Human thymus cells (O10) andrecombinant human CD1a protein (C1A/711) were used as the immunogens for this antibody cocktail.
    Klon
    O10-C1A-711
    Isotyp
    IgG1 kappa
    Top Product
    Discover our top product CD1a Primärantikörper
  • Applikationshinweise
    The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the antibody to be titered up or down for optimal performance.

    1. Staining of formalin-fixed tissues requires boiling tissue sections in 10  mM Citrate Buffer,  pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes.
    2. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.\. Prediluted IHC only format : incubate for 30 min at RT (2)

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Prediluted in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide, *For IHC use only*
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store the CD1a antibody cocktail at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
  • Target
    CD1a
    Andere Bezeichnung
    CD1a (CD1a Produkte)
    Synonyme
    CD1 antikoerper, FCB6 antikoerper, HTA1 antikoerper, R4 antikoerper, T6 antikoerper, CD1A antikoerper, CD1a molecule antikoerper, CD1 antigen antikoerper, T-cell surface glycoprotein CD1a antikoerper, CD1A antikoerper, CD1.1 antikoerper, LOC100156095 antikoerper, LOC101111409 antikoerper
    Hintergrund
    At least five CD1 genes (CD1a, b, c, d, and e) are identified. CD1 proteins have been demonstrated to restrict T cell response to non-peptide lipid and glycolipid antigens and play a role in non-classical antigen presentation. CD1a is a non-polymorphic MHC Class 1 related cell surface glycoprotein, expressed in association with Beta-2 microglobulin. CD1a antibody labels Langerhans cell histiocytosis (Histiocytosis X), extranodal histiocytic sarcoma, a subset of T-lymphoblastic lymphoma/leukemia, and interdigitating dendritic cell sarcoma of the lymph node. When combined with antibody against TTF-1 and CD5, CD1a antibody is useful in distinguishing between pulmonary and thymic neoplasms since CD1a is consistently expressed in thymic lymphocytes in both typical and atypical thymomas, but only focally in 1/6 of thymic carcinomas and not in lymphocytes in pulmonary neoplasms. antibody to CD1a is reported to be a new marker for perivascular epithelial cell tumor (PEComa).
    Gen-ID
    909
    Pathways
    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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