STRADB Antikörper (Internal Region)

Produktnummer ABIN3024145

Produktdetails anti-STRADB Antikörper

Target: STRADB (STE20-Related Kinase Adaptor beta (STRADB))

Bindungsspezifität: Internal Region

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser STRADB Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: Protein A affinity chromatography

Immunogen: A recombinant protein fragment from the interior region of human Als2Cr2 was used as the immunogen for this antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Provided assay concentrations are suggestions only, Als2Cr2 antibody titration may be required for optimal results. This antibody will detect the 418 (ILPIP alpha) and 280 (ILPIP beta) amino acid isoforms.\. Western blot: 5-10 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: 0.5 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the Als2Cr2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Details zu STRADB

Target: STRADB (STE20-Related Kinase Adaptor beta (STRADB))

Andere Bezeichnung: Als2Cr2 (STRADB Produkte)

Synonyme: Als2cr2 antikoerper, RGD1559449 antikoerper, als2cr2 antikoerper, MGC82468 antikoerper, STRADB antikoerper, ALS2CR2 antikoerper, AA792893 antikoerper, B830008M19 antikoerper, D1Ucla2 antikoerper, ILPIP antikoerper, ILPIPA antikoerper, PRO1038 antikoerper, Papk antikoerper, Syradb antikoerper, CALS-21 antikoerper, PAPK antikoerper, STE20-related kinase adaptor beta antikoerper, STE20-related kinase adaptor beta L homeolog antikoerper, Stradb antikoerper, STRADB antikoerper, stradb.L antikoerper

Hintergrund: Als2Cr2, also called STE20-related kinase adapter protein beta (STRAD beta) and ILPIP, is a serine/threonine protein kinase encoded by the STRADB gene, discovered as an XIAP interacting protein. It is a mediator of the XIAP/TAK1 activation of the JNK1 pathway, an apoptosis inhibition mechanism independent of XIAP inhibition of caspases. Alone, it only moderately activates JNKs, but its interaction with XIAP/TAK1 induces a much stronger activation of JNK1, protecting against Caspase 1- or Fas-induced apoptosis.

Gen-ID: 55437

Pathways: AMPK Signaling