VWF Antikörper
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- Target Alle VWF Antikörper anzeigen
- VWF (Von Willebrand Factor (VWF))
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser VWF Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Aufreinigung
- Protein G purified
- Immunogen
- A recombinant human protein fragment was used as the immunogen for this von Willebrand Factor antibody.
- Klon
- WFA52-2
- Isotyp
- IgG1 kappa
- Top Product
- Discover our top product VWF Primärantikörper
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- Applikationshinweise
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Variations in protocols, secondaries and substrates may require the von Willebrand Factor antibody to be titered for optimal performance.
1. FFPE staining requires boiling tissue sections in 10 mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes.\. FACS: 0.5-1 μg/million cells,IF: 0.5-1 μg/mL,WB: 0.5-1.0 μg/mL,IHC (FFPE): 0.5-1.0 μg/mL for 30 minutes at RT (1)
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 0.2 mg/mL
- Buffer
- 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Store the von Willebrand Factor antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
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- Target
- VWF (Von Willebrand Factor (VWF))
- Andere Bezeichnung
- Von Willebrand Factor (VWF Produkte)
- Synonyme
- VWF antikoerper, si:ch1073-474e24.1 antikoerper, F8VWF antikoerper, VWD antikoerper, 6820430P06Rik antikoerper, AI551257 antikoerper, B130011O06Rik antikoerper, C630030D09 antikoerper, von Willebrand factor antikoerper, Von Willebrand factor antikoerper, VWF antikoerper, vwf antikoerper, Vwf antikoerper
- Hintergrund
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Von Willebrand Factor (vWF) is a glycoprotein produced by bone marrow cells and endothelial cells lining the inside surface of blood vessels. Its primary function is platelet adhesion, binding to Factor VIII, collagen and platelets, to coagulate blood at the site of wounding. The enzyme VWFCP, or vWF-cleaving protease, facilitates clotting by cutting the protein into subunits, increasing its binding capacity.
Deficiency or dysfunction of the protein increases the tendency of wounds to bleed, or to bleed more. Over 300 gene mutations have been identified and classified into three types. Type 1 von Willebrand Factor disease is characterized by reduced amounts in the bloodstream, Type 2 by reduced binding ability and Type 3 by a nonfunctional protein.
- Gen-ID
- 7450
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