UACA Antikörper
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- Target Alle UACA Antikörper anzeigen
- UACA
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Reaktivität
- Human, Maus
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser UACA Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)
- Aufreinigung
- Protein G affinity chromatography
- Immunogen
- Nuclei of myeloid leukemia biopsy cells were used as the immunogen for the UACA antibody.
- Klon
- AE-5
- Isotyp
- IgG1 kappa
- Top Product
- Discover our top product UACA Primärantikörper
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- Applikationshinweise
- Optimal dilution of the UACA antibody should be determined by the researcher.\. Flow Cytometry: 0.5-1 μg/million cells in 0.1ml,Immunofluorescence: 0.5-1 μg/mL,Western blot: 0.5-1 μg/mL
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 0.2 mg/mL
- Buffer
- 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Store the UACA antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
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- Target
- UACA
- Andere Bezeichnung
- UACA (UACA Produkte)
- Synonyme
- NUCLING antikoerper, 2700059D02Rik antikoerper, nucling antikoerper, RGD1560011 antikoerper, uveal autoantigen with coiled-coil domains and ankyrin repeats antikoerper, UACA antikoerper, Uaca antikoerper
- Hintergrund
- UACA (Uveal Autoantigen with Coiled-coil domains and Ankyrin repeats) is a 1,416 amino acid nuclear membrane protein. It was originally identified as an autoantigen in patients with panuveitis, a characteristic of Vogt-Koyanagi-Harada disease, and in patients with Graves' disease. UACA was also later identified as Nucling, an mRNA differentially expressed in F9 embryonal carcinoma cells during cardiac muscle differentiation. UACA appears to function as a pro-apoptotic protein that recruits the apaf-1-pro-caspase-9 complex for the induction of apoptosis to mediate the cell-death pathway.
- Pathways
- Positive Regulation of Endopeptidase Activity
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