DNMT1 Antikörper (pSer714)

Produktnummer ABIN3023526

Produktdetails anti-DNMT1 Antikörper

Target: DNMT1 (DNA (Cytosine-5)-Methyltransferase 1 (DNMT1))

Bindungsspezifität: pSer714

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DNMT1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Sequenz: MPSPK

Kreuzreaktivität: Human

Produktmerkmale: Phosphorylated Antibodies

Aufreinigung: Affinity purification

Immunogen: A synthetic phosphorylated peptide around S714 of human Phospho-DNMT1-pS714 (NP_001370.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IF,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid freeze / thaw cycles

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu DNMT1

Target: DNMT1 (DNA (Cytosine-5)-Methyltransferase 1 (DNMT1))

Andere Bezeichnung: DNMT1 (DNMT1 Produkte)

Synonyme: cb1075 antikoerper, cb983 antikoerper, dmnt1 antikoerper, fb05h01 antikoerper, mta antikoerper, wu:fb05h01 antikoerper, ADCADN antikoerper, AIM antikoerper, CXXC9 antikoerper, DNMT antikoerper, HSN1E antikoerper, MCMT antikoerper, DDM2 antikoerper, DECREASED DNA METHYLATION 2 antikoerper, DMT01 antikoerper, DMT1 antikoerper, DNA METHYLTRANSFERASE antikoerper, DNA METHYLTRANSFERASE 01 antikoerper, DNA METHYLTRANSFERASE 1 antikoerper, MET2 antikoerper, METHYLTRANSFERASE 2 antikoerper, METHYLTRANSFERASE I antikoerper, METI antikoerper, methyltransferase 1 antikoerper, Cxxc9 antikoerper, Dnmt antikoerper, Dnmt1o antikoerper, MTase antikoerper, Met-1 antikoerper, Met1 antikoerper, MommeD2 antikoerper, m.MmuI antikoerper, DNA methyltransferase 1 antikoerper, DNA (cytosine-5-)-methyltransferase 1 antikoerper, methyltransferase 1 antikoerper, DNA methyltransferase (cytosine-5) 1 antikoerper, DNMT1 antikoerper, dnmt1 antikoerper, Dnmt1 antikoerper, MET1 antikoerper

Hintergrund: This gene encodes an enzyme that transfers methyl groups to cytosine nucleotides of genomic DNA. This protein is the major enzyme responsible for maintaining methylation patterns following DNA replication and shows a preference for hemi-methylated DNA. Methylation of DNA is an important component of mammalian epigenetic gene regulation. Aberrant methylation patterns are found in human tumors and associated with developmental abnormalities. Variation in this gene has been associated with cerebellar ataxia, deafness, and narcolepsy, and neuropathy, hereditary sensory, type IE. Alternative splicing results in multiple transcript variants.,ADCADN,AIM,CXXC9,DNMT,HSN1E,MCMT,m.HsaI,DNMT1,Epigenetics & Nuclear Signaling,Chromatin Modifying Enzymes,DNA methylation,Protein phosphorylation,DNMT1

Molekulargewicht: 144 kDa/183 kDa/184 kDa

Gen-ID: 1786

UniProt: P26358

Pathways: SARS-CoV-2 Protein Interaktom, Phosphorylierungen bei SARS-CoV-2 Infektion