Recombinant fusion protein containing a sequence corresponding to amino acids 21-180 of human Pro-glucagon (NP_002045.1).
Isotyp
IgG
Applikationshinweise
IHC,1:100 - 1:200,IF,1:100 - 1:200
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Buffer
PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung
Avoid freeze / thaw cycles
Lagerung
-20 °C
Informationen zur Lagerung
Store at -20°C. Avoid freeze / thaw cycles.
Target
Pro-Glucagon
Hintergrund
The protein encoded by this gene is actually a preproprotein that is cleaved into four distinct mature peptides. One of these, glucagon, is a pancreatic hormone that counteracts the glucose-lowering action of insulin by stimulating glycogenolysis and gluconeogenesis. Glucagon is a ligand for a specific G-protein linked receptor whose signalling pathway controls cell proliferation. Two of the other peptides are secreted from gut endocrine cells and promote nutrient absorption through distinct mechanisms. Finally, the fourth peptide is similar to glicentin, an active enteroglucagon.,GCG,GLP-1,GLP1,GLP2,GRPP,glucagon,Cancer,Signal Transduction,Endocrine & Metabolism,Endocrine and metabolic diseases,Diabetes,Neuroscience,Stem Cells,Cardiovascular,Heart,Cardiovascular diseases,Heart disease,Pro-glucagon