kappa Light Chain Antikörper (PE)

Produktnummer ABIN302034

Produktdetails anti-kappa Light Chain Antikörper (PE)

Target: kappa Light Chain

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser kappa Light Chain Antikörper ist konjugiert mit PE

Applikation: Flow Cytometry (FACS)

Spezifität: The mouse monoclonal antibody A8B5 reacts with kappa light chains (22.5 kDa) of immunoglobulins.

Keine Kreuzreaktivität: Ziege, Meerschweinchen, Hamster, Kaninchen, Schaf

Kreuzreaktivität (Details): Human

Aufreinigung: Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

Klon: A8B5

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Flow cytometry: The reagent is designed for analysis of human blood cells using 20 μL reagent / 100 μL of whole blood or 10⁶ cells in a suspension. The content of a vial (2 ml) is sufficient for 100 tests.

Kommentare:

The purified antibody is conjugated with R-Phycoerythrin (PE) under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use. No reconstitution is necessary.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Rekonstitution: No reconstitution is necessary.

Buffer: Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Do not freeze.
Avoid prolonged exposure to light.

Lagerung: 4 °C

Informationen zur Lagerung: Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.

Referenzen für anti-kappa Light Chain Antikörper (PE) (ABIN302034)

Scheeren, Diehl, Smit, Beaumont, Naspetti, Bende, Blom, Karube, Ohshima, van Noesel, Spits: "IL-21 is expressed in Hodgkin lymphoma and activates STAT5: evidence that activated STAT5 is required for Hodgkin lymphomagenesis." in: Blood, Vol. 111, Issue 9, pp. 4706-15, (2008) (PubMed).

Diaz de Domingo, Lardo, Romero Artaza, Merelli, Carbia, Sánchez Avalos: "[Immunocytochemistry techniques for the diagnosis of hematologic neoplasms]." in: Medicina, Vol. 59, Issue 1, pp. 11-6, (1999) (PubMed).

Konig, Wennemuth, Soyer, Hoffmann, Happle, Krause: "Vulvar amyloidosis mimicking giant condylomata acuminata in a patient with multiple myeloma." in: European journal of dermatology : EJD, Vol. 9, Issue 1, pp. 29-31, (1999) (PubMed).

Details zu kappa Light Chain

Target: kappa Light Chain

Andere Bezeichnung: Kappa light chains (kappa Light Chain Produkte)

Synonyme: LOC100037688 antikoerper, B128L antikoerper, B55L antikoerper, IgK antikoerper, TCRAV31S1 antikoerper, TCRAV40S1 antikoerper, kappa light chain antikoerper, immunoglobulin kappa chain variable 8 (V8) antikoerper, T cell receptor alpha variable 40 antikoerper, LOC100037688 antikoerper, Igk-V8 antikoerper, TRAV40 antikoerper

Hintergrund: Immunoglobulin classes share the same basic four polypeptide chain structure of two heavy chains (five heavy chains types) and two light chains (kappa, lambda, both having a molecular weight of 22.5 kDa). Kappa and lambda consist of a variable region and a constant region and can easily be differentiated by the antigenic properties of the constant region. The ratio of kappa to lambda is 70:30.,Immunoglobulin kappa, Igk