ADRB3 Antikörper

Produktnummer ABIN290046

Produktdetails anti-ADRB3 Antikörper

Target: ADRB3 (Adrenergic, beta-3-, Receptor (ADRB3))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ADRB3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: This antibody was prepared from the serum of a rabbit immunized with a partial peptide representing the C-terminal domain of Human beta3-AR, and purified by peptide affinity chromatography.

Immunogen: Partial peptide of Human beta3-AR

Anwendungsinformationen

Applikationshinweise: Working dilution For Western blotting: 5.0ug/ml

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.25 mg/ml

Buffer: PBS (containing 2% Block Ace as a stabilizer, 0.1% Proclin as a bacteriostat)

Konservierungsmittel: ProClin

Lagerung: -20 °C

Details zu ADRB3

Target: ADRB3 (Adrenergic, beta-3-, Receptor (ADRB3))

Andere Bezeichnung: beta3-AR (ADRB3 Produkte)

Synonyme: BETA3AR antikoerper, Adrb-3 antikoerper, ADRB antikoerper, BAR3 antikoerper, B3AR antikoerper, GPCR antikoerper, im:7154935 antikoerper, si:ch211-215f19.1 antikoerper, zgc:194843 antikoerper, zgc:194852 antikoerper, adrenoceptor beta 3 antikoerper, adrenergic receptor, beta 3 antikoerper, adrenoceptor beta 3a antikoerper, adrenoceptor beta 3b antikoerper, ADRB3 antikoerper, Adrb3 antikoerper, adrb3a antikoerper, adrb3b antikoerper

Hintergrund: The neurotransmitter/hormone adrenaline (epinephrine, adrenalin) plays a central role in the mammalianstress response, increasing heart rate, raising blood pressure, and increasing blood glucose levels upon enteringthe blood stream.Adrenaline is secreted primarily by the adrenal medulla. Adrenaline activates both alpha-adrenergic receptors and beta-adrenergic receptors. Three subtypes of beta adrenergic receptors are known, beta1, beta2, beta3, expressed primarily inheart, respiratory tissue, and adipose tissue, respectively. Beta3-receptors are particularly abundant in brown adipocytes and play important roles in lipolysis andtheremoregulation. (Ref.1, Ref.2) Recently this receptor has received attention from researchers intereseted in type 2diabetes mellitus and obesity. It is also being considered as a therapertic target for heart failure (Ref.3).

Pathways: cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling, Feeding Behaviour, Brown Fat Cell Differentiation