PER3 Antikörper

Produktnummer ABIN289981

Produktdetails anti-PER3 Antikörper

Target: PER3 (Period Homolog 3 (PER3))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PER3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: ProteinG Affinity Purified

Immunogen: GST-Human PERIOD3 fusion Protein

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/ml

Buffer: PBS (containing 2% Block Ace as a stabilizer, 0.1% Proclin as a bacteriostat)

Konservierungsmittel: ProClin

Lagerung: -20 °C

Details zu PER3

Target: PER3 (Period Homolog 3 (PER3))

Andere Bezeichnung: PERIOD3 (PER3 Produkte)

Synonyme: period3 antikoerper, rper3 antikoerper, GIG13 antikoerper, 2810049O06Rik antikoerper, mPer3 antikoerper, period circadian clock 3 antikoerper, period circadian regulator 3 antikoerper, Per3 antikoerper, PER3 antikoerper

Hintergrund: Most organisms show circadian 24-h rhythmicity in their behavior and phsysiology. In mammals,biological clock is located in the suprachiasmatic nucleus (SCN), generates circadian rhythms in behaviourand physiology. These biological rhythms are adjusted daily to the environmental light/dark cycle via theretinohypothalamic tract (RHT). Three mammalian priod genes (per1, per2, and per3) that resemble theclock-regulating gene of Dorosophia melangaster, period (per ), have been cloned. Circadian clocks arealso located in peripheral tissues of mammals that are synchronized by the SCN. A molecular description ofthe mammalian circadian system has revealed that circadian oscillations may be a fundamental property ofmany cells in the body.Recently, it has been shown that the phosphorylation of PER proteins by casein kinase Iepsilon can modulatethe nuclear localization of mPER1 and mPER3 but not of mPER2.This antibody is useful tool to clarify molecular functions that regulate biological clock.