SLC22A9 Antikörper

Produktnummer ABIN289969

Produktdetails anti-SLC22A9 Antikörper

Target: SLC22A9 (Solute Carrier Family 22 (Organic Anion Transporter), Member 9 (SLC22A9))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SLC22A9 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Aufreinigung: This antibody was purified from rabbit serum immunized with synthesized C-end peptide of human OAT4 by peptide affinity chromatography.

Immunogen: Partial peptide of Human Organic Anion Transporter 4 (OAT4)

Anwendungsinformationen

Applikationshinweise: Working dilution for immunohistochemistry: 1-5ug/ml

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.1 mg/ml

Buffer: PBS (containing 2% Block Ace as a stabilizer, 0.1% Proclin as a bacteriostat)

Konservierungsmittel: ProClin

Lagerung: -20 °C

Details zu SLC22A9

Target: SLC22A9 (Solute Carrier Family 22 (Organic Anion Transporter), Member 9 (SLC22A9))

Andere Bezeichnung: Organic Anion Transporter 4 (OAT4) (SLC22A9 Produkte)

Synonyme: HOAT4 antikoerper, OAT4 antikoerper, OAT7 antikoerper, UST3H antikoerper, ust3 antikoerper, SLC22A25 antikoerper, solute carrier family 22 member 9 antikoerper, solute carrier family 22 (organic anion transporter), member 9 antikoerper, SLC22A9 antikoerper

Hintergrund: To eliminate the drug, xenobiotics, a varirety of endogeneous substances, and their metabolites out of thebody, specific membrane proteins named transporters are required. There are two major pathways for theelimination, one of which is hepatic one through bile, and another is renal one to urine. The transporter fallinto various transport systems by the transportative substrate. In particular, oraganic ion transporter familyis comprised of organic anion transport family (OAT), oraganic cation transport family (OCT),OCTN/carnitine transport family, and OAT are multispecific organic anion transpoters, the substrates ofwhich include a lot of both endogeneous and exogeneous anions.Human organic anion transporter 4 (OAT4) encodes a 550 amino acid residue protein, and is predicted 12putative membrane-spanning protein. OAT4 mediates the high-affinity Na+-independent transport ofesteron sulfate, dehydroepiandrosterone (DHEA) sulfate, and ochratoxin A, p-aminohippurate (PAH).OAT4 is expressed in the kidney and placenta. OAT4 might be responsible for the elimination anddetoxification of harmful anionic sybstances from the fetus.This antidody has been proved to be useful for immunohistochemistry .