SLC22A8 Antikörper

Produktnummer ABIN289968

Produktdetails anti-SLC22A8 Antikörper

Target: SLC22A8 (Solute Carrier Family 22 (Organic Anion Transporter), Member 8 (SLC22A8))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SLC22A8 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Aufreinigung: This antibody was purified from rabbit serum immunized with synthesized C-end peptide of human OAT3 by peptide affinity chromatography.

Immunogen: Partial peptide of Human Organic Anion Transporter 3 (OAT3)

Anwendungsinformationen

Applikationshinweise: Working dilution for immunohistochemistry 1-5ug/ml

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.1 mg/ml

Buffer: PBS (containing 2% Block Ace as a stabilizer, 0.1% Proclin as a bacteriostat)

Konservierungsmittel: ProClin

Lagerung: -20 °C

Details zu SLC22A8

Target: SLC22A8 (Solute Carrier Family 22 (Organic Anion Transporter), Member 8 (SLC22A8))

Andere Bezeichnung: Organic Anion Transporter 3 (OAT3) (SLC22A8 Produkte)

Synonyme: OAT3 antikoerper, Oat3 antikoerper, Roct antikoerper, OCT3 antikoerper, solute carrier family 22 member 8 antikoerper, solute carrier family 22 (organic anion transporter), member 8 antikoerper, SLC22A8 antikoerper, Slc22a8 antikoerper

Hintergrund: To eliminate the drug, xenobiotics, a varirety of endogeneous substances, and their metabolites out of thebody, specific membrane proteins named transporters are required. There are two major pathways for theelimination, one of which is hepatic one through bile, and another is renal one to urine. The transporter fallinto various transport systems by the transportative substrate. In particular, oraganic ion transporter familyis comprised of organic anion transport family (OAT), oraganic cation transport family (OCT),OCTN/carnitine transport family, and OAT are multispecific organic anion transpoters, the substrates ofwhich include a lot of both endogeneous and exogeneous anions.Human organic anion transporter 3 (OAT3) encodes a 543 amino acid residue protein, and which ispredicted 12 putative membran-spanning protein. OAT3 is expressed in the kidney, brain, and skeletalmuscle. OAT3 mediated the uptake of organic anions, such as PAH (p-aminohippurate), ochratoxin A andestrone sulfate, prostaglandin E2 (PGE2 ), and cimetidine.This has been proved to be useful for immunohistochemistry .